Evaluating the Evidence for Neuroprotective and Axonal Regenerative Activities of Different Inflammatory Cell Types After Optic Nerve Injury

AW Venanzi, LD McGee, AS Hackam - Molecular neurobiology, 2024 - Springer
The optic nerve contains retinal ganglion cell (RGC) axons and functions to transmit visual
stimuli to the brain. Injury to the optic nerve from ischemia, trauma, or disease leads to …

Augmenting fibronectin levels in injured adult CNS promotes axon regeneration in vivo

A Lukomska, BA Rheaume, MP Frost, WC Theune… - Experimental …, 2024 - Elsevier
In an attempt to repair injured central nervous system (CNS) nerves/tracts, immune cells are
recruited into the injury site, but endogenous response in adult mammals is insufficient for …

The role of monocytes in optic nerve injury

X Liu, Y Liu, MM Khodeiry, RK Lee - Neural regeneration …, 2023 - journals.lww.com
Monocytes, including monocyte-derived macrophages and resident microglia, mediate
many phases of optic nerve injury pathogenesis. Resident microglia respond first, followed …

Microglial CD11b knockout contributes to axonal debris clearance and axonal degradation attenuation via IGF-1 after acute optic nerve injury

J Zhou, S Lin, Q Hu, X Li, X Chen, L Luo… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Microglial clearance of axonal debris is an essential response for management of
traumatic optic neuropathy. Inadequate removal of axonal debris leads to increased …

单核细胞在视神经损伤中的作用

X Liu, Y Liu, MM Khodeiry, RK Lee - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Monocytes, including monocyte-derived macrophages and resident microglia, mediate
many phases of optic nerve injury pathogenesis. Resident microglia respond first, followed …

Macrophages Modulate Optic Nerve Crush Injury Scar Formation and Retinal Ganglion Cell Function

Y Liu, X Liu, CA Dorizas, Z Hao… - … ophthalmology & visual …, 2024 - iovs.arvojournals.org
Purpose: Optic nerve (ON) injuries can result in vision loss via structural damage and
cellular injury responses. Understanding the immune response, particularly the role of …