Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Natural killer (NK) cells can defend an organism against a variety of threats, probably using
several different strategies to discriminate between normal and~ berrant cells. According to …

T cells that accompany allogeneic hematopoietic grafts for treating leukemia enhance
engraftment and mediate the graft-versus-leukemia effect. Unfortunately, alloreactive T cells …

▪ Abstract NK cells are regulated by opposing signals from receptors that activate and inhibit
effector function. While positive stimulation may be initiated by an array of co-stimulatory …

▪ Abstract Natural killer cells are likely to play an important role in the host defenses because
they kill virally infected or tumor cells but spare normal self-cells. The molecular mechanism …

Natural killer (NK) cells, similar to other lymphocytes, acquire tolerance to self. This means
that NK cells have the potential to attack normal self cells but that there are mechanisms to …

Mice homozygous for a β2-microglobulin gene disruption do not express any detectable β2-
ITL protein. They express little if any functional major histocompatibility complex (MHC) class …

The expression of KIR and CD94: NKG2 receptors was determined for more than 100
natural killer (NK) cell clones obtained from two blood donors who differ in their HLA class I …

IRRADIATED MHC-heterozygous mice often reject bone marrow cells transplanted from one
of the homozygous parental strains, a phenomenon ('hybrid resistance') that appears to …