Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Inflammation is a hallmark of stroke pathology. The cytokines, tumor necrosis factor (TNF),
interleukin (IL)-1, and IL-6, modulate tissue injury in experimental stroke and are therefore …

Background The brain's initial innate response to stroke is primarily mediated by microglia,
the resident macrophage of the CNS. However, as early as 4 h after stroke, the blood–brain …

The aims of this study were to examine the alternation in serum exosome concentrations
and the levels of serum exosomal miR-9 and miR-124, two brain-specific miRNAs, in acute …

Background and Purpose—The proinflammatory cytokine IL-1 (interleukin-1) has a
deleterious role in cerebral ischemia, which is attenuated by IL-1 receptor antagonist (IL …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

The innate immune system plays a dualistic role in the evolution of ischemic brain damage
and has also been implicated in ischemic tolerance produced by different conditioning …

After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

The past 2 decades have seen a revolution in our approach to therapeutic
immunosuppression. We have moved from relying on broadly active traditional medications …

Background and Purpose—Adult stem cell therapy is an experimental stroke treatment.
Here, we assessed homing and anti-inflammatory effects of bone marrow stromal cells …