[HTML][HTML] Editor's choice--European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of asymptomatic lower limb peripheral …

J Nordanstig, CA Behrendt, I Baumgartner… - European Journal of …, 2024 - Elsevier
BIOTRONIK's First in Man study of the Passeo-18 LUX drug releasing PTA Balloon Catheter
vs. the uncoated Passeo-18 PTA balloon catheter in subjects requiring revascularisation of …

Characteristics of atherosclerosis in femoropopliteal artery and its clinical relevance

P Poredoš, M Cevc, A Blinc - Atherosclerosis, 2021 - Elsevier
Atherosclerosis is a systemic disease with different faces. Despite identical or similar
pathogenetic mechanisms, atherosclerotic lesions and their clinical manifestations vary in …

Relationship between serum homocysteine, fibrinogen, lipoprotein-a level, and peripheral arterial disease: a dose–response meta-analysis

H Wang, P Wu, D Jiang, H Zhang, J Zhang… - European Journal of …, 2022 - Springer
Aim At present, the relationship between serum homocysteine (Hcy), fibrinogen (FIB),
lipoprotein-a (LPa), and PAD is uncertain, and there has been no meta-analysis to establish …

Lipoprotein (a): Pathophysiology, measurement, indication and treatment in cardiovascular disease. A consensus statement from the Nouvelle Société Francophone d' …

V Durlach, D Bonnefont-Rousselot, F Boccara… - Archives of …, 2021 - Elsevier
Lipoprotein (a) is an apolipoprotein B100-containing low-density lipoprotein-like particle that
is rich in cholesterol, and is associated with a second major protein, apolipoprotein (a) …

Lipid-lowering drugs and inflammatory bowel disease's risk: a drug-target Mendelian randomization study

J Zhao, R Chen, M Luo, H Gong, K Li… - Diabetology & Metabolic …, 2024 - Springer
Background Inflammatory bowel disease (IBD) has been associated with lipid-lowering
drugs in observational studies. Drug-target Mendelian randomization (MR) was utilized in …

Modeling cholesterol metabolism and atherosclerosis

MT Mc Auley - WIREs Mechanisms of Disease, 2022 - Wiley Online Library
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and
mortality among Western populations. Many risk factors have been identified for ASCVD; …

Circulating proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with disease activity and risk of incident cardiovascular disease in patients with …

CC Mok, LY Ho, KL Chan, SM Tse, CH To - Inflammation, 2023 - Springer
To study the relationship of serum PCSK9 and disease activity and major adverse
cardiovascular events (MACEs) in systemic lupus erythematosus (SLE). Consecutive …

[HTML][HTML] Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in white populations

A Kheirkhah, JF Schachtl-Riess, C Lamina, S Di Maio… - Atherosclerosis, 2023 - Elsevier
Background and aims Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key
regulator of lipid homeostasis. A few earlier genome-wide association studies (GWAS) …

Use of lipid-lowering therapy: the guidelines, the drugs or the patient?

C Borghi, A Bragagni - European Heart Journal Supplements, 2022 - academic.oup.com
The current step up approach in the therapy of dyslipidemias aims to reduce the amount of
LDL cholesterol below a threshold that varies according to the patient's risk category, with a …

PCSK9 and inflammation: their role in autoimmune diseases, with a focus on rheumatoid arthritis and systemic lupus erythematosus

S Ministrini, F Carbone - Current Medicinal Chemistry, 2022 - ingentaconnect.com
Despite a clear epidemiological link between autoimmune disease and cardiovascular (CV)
risk exists, pathophysiological explanations are extremely complex and far from being …