The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

The biofilm matrix: multitasking in a shared space

HC Flemming, ED van Hullebusch, TR Neu… - Nature Reviews …, 2023 - nature.com
The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …

[HTML][HTML] Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

[HTML][HTML] Pseudomonas aeruginosa Biofilms

MTT Thi, D Wibowo, BHA Rehm - International journal of molecular …, 2020 - mdpi.com
Pseudomonas aeruginosa is an opportunistic human pathogen causing devastating acute
and chronic infections in individuals with compromised immune systems. Its highly notorious …

[HTML][HTML] Biofilms: the microbial “protective clothing” in extreme environments

W Yin, Y Wang, L Liu, J He - International journal of molecular sciences, 2019 - mdpi.com
Microbial biofilms are communities of aggregated microbial cells embedded in a self-
produced matrix of extracellular polymeric substances (EPS). Biofilms are recalcitrant to …

[HTML][HTML] Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention

Z Khatoon, CD McTiernan, EJ Suuronen, TF Mah… - Heliyon, 2018 - cell.com
In living organisms, biofilms are defined as complex communities of bacteria residing within
an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the …

Mechanomicrobiology: how bacteria sense and respond to forces

YF Dufrêne, A Persat - Nature Reviews Microbiology, 2020 - nature.com
Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa

LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Bacterial extracellular polysaccharides in biofilm formation and function

DH Limoli, CJ Jones, DJ Wozniak - Microbial Biofilms, 2015 - Wiley Online Library
The ability to construct and maintain a structured multicellular bacterial community depends
critically on the production of extracellular matrix components (1, 2). While the biofilm matrix …

[HTML][HTML] Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

LK Jennings, JE Dreifus, C Reichhardt, KM Storek… - Cell reports, 2021 - cell.com
In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called
biofilms that are thought to contribute to chronic infection. To form aggregates, P. aeruginosa …