Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Raman spectroscopy of biological tissues

ACS Talari, Z Movasaghi, S Rehman… - Applied spectroscopy …, 2015 - Taylor & Francis
We previously published a comprehensive review paper reviewing the Raman spectroscopy
of biological molecules. This research area has expanded rapidly, which warranted an …

Using Raman spectroscopy to characterize biological materials

HJ Butler, L Ashton, B Bird, G Cinque, K Curtis… - Nature protocols, 2016 - nature.com
Raman spectroscopy can be used to measure the chemical composition of a sample, which
can in turn be used to extract biological information. Many materials have characteristic …

Chemically sensitive bioimaging with coherent Raman scattering

CH Camp Jr, MT Cicerone - Nature photonics, 2015 - nature.com
Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Single-cell metabolomics: analytical and biological perspectives

R Zenobi - Science, 2013 - science.org
Background In recent years, there has been a surge in the development and application of
single-cell genomics, transcriptomics, proteomics, and metabolomics. The metabolome is …

Stimulated Raman scattering: from bulk to nano

RC Prince, RR Frontiera, EO Potma - Chemical reviews, 2017 - ACS Publications
Stimulated Raman scattering (SRS) describes a family of techniques first discovered and
developed in the 1960s. Whereas the nascent history of the technique is parallel to that of …

Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy

M Ji, DA Orringer, CW Freudiger… - Science translational …, 2013 - science.org
Surgery is an essential component in the treatment of brain tumors. However, delineating
tumor from normal brain remains a major challenge. We describe the use of stimulated …

High-speed coherent Raman fingerprint imaging of biological tissues

CH Camp Jr, YJ Lee, JM Heddleston, CM Hartshorn… - Nature …, 2014 - nature.com
An imaging platform based on broadband coherent anti-Stokes Raman scattering has been
developed that provides an advantageous combination of speed, sensitivity and spectral …

High-speed molecular spectral imaging of tissue with stimulated Raman scattering

Y Ozeki, W Umemura, Y Otsuka, S Satoh… - Nature …, 2012 - nature.com
To date, medical imaging of tissues has largely relied on time-consuming staining
processes, and there is a need for rapid, label-free imaging techniques. Stimulated Raman …

Label-free DNA imaging in vivo with stimulated Raman scattering microscopy

FK Lu, S Basu, V Igras, MP Hoang… - Proceedings of the …, 2015 - National Acad Sciences
Label-free DNA imaging is highly desirable in biology and medicine to perform live imaging
without affecting cell function and to obtain instant histological tissue examination during …