Maintenance of genome stability requires control over the expression of transposable
elements (TEs), whose activity can have substantial deleterious effects on the host …

Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …

The discovery of N6-methyldeoxyadenine (6mA) across eukaryotes led to a search for
additional epigenetic mechanisms. However, some studies have highlighted confounding …

Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA.
Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is …

Abstract Motivation The Oxford Nanopore sequencing enables to directly detect methylation
states of bases in DNA from reads without extra laboratory techniques. Novel computational …

Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine
and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of …

Advances in the detection and mapping of messenger RNA (mRNA) N 6-methyladenosine
(m 6 A) and 5-methylcytosine (m 5 C), and DNA N 6-methyldeoxyadenosine (6mA) …

N 6-methyladenine (6mdA) is a widespread DNA modification in bacteria. More recently,
6mdA has also been characterized in mammalian DNA. However, measurements of 6mdA …

Sequencing technologies are evolving at a rapid pace, enabling the generation of massive
amounts of data in multiple dimensions (eg, genomics, epigenomics, transcriptomic …

Chemical modifications to nucleic acids occur across the kingdoms of life and carry
important regulatory information. Reliable high-resolution mapping of these modifications is …