Salivary biomarkers and their application in the diagnosis and monitoring of the most common oral pathologies

L Melguizo-Rodríguez, VJ Costela-Ruiz… - International journal of …, 2020 - mdpi.com
Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner—
and the results of its analysis complement clinical and histopathological findings in the …

Artificial intelligence in salivary biomarker discovery and validation for oral diseases

J Adeoye, YX Su - Oral Diseases, 2024 - Wiley Online Library
Salivary biomarkers can improve the efficacy, efficiency, and timeliness of oral and
maxillofacial disease diagnosis and monitoring. Oral and maxillofacial conditions in which …

[HTML][HTML] Salivary IL-1β, IL-6, and IL-10 Are Key Biomarkers of Periodontitis Severity

M Relvas, A Mendes-Frias, M Gonçalves… - International Journal of …, 2024 - mdpi.com
To explore severity and progression biomarkers, we examined the clinical relevance of
multiple cytokines and mediators involved in the inflammatory response in periodontitis. A …

[HTML][HTML] Development of ferroptosis-associated ceRNA network in periodontitis

C Zhang, P Xue, J Ke, Q Cai - international dental journal, 2023 - Elsevier
Objectives Periodontitis is a chronic inflammatory illness that may lead to tooth loosening
and even loss, and its pathogenesis is not fully understood. Ferroptosis is an iron …

IL-1 superfamily members and periodontal diseases

E Papathanasiou, P Conti, F Carinci… - Journal of Dental …, 2020 - journals.sagepub.com
Periodontitis is a complex, multifactorial chronic disease involving continuous interactions
among bacteria, host immune/inflammatory responses, and modifying genetic and …

Evaluation of salivary biomarkers of periodontal disease based on smoking status: a systematic review

J Noh, JH Jang, HS Yoon, KB Kim, MH Heo… - International Journal of …, 2022 - mdpi.com
Saliva is a useful biomarker for diagnosing oral health conditions, including periodontal
disease (PD). Smoking is a risk factor for PD. The aim of this systematic review was to …

Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis

T Blanco-Pintos, A Regueira-Iglesias… - Periodontitis: Advances …, 2022 - Springer
Periodontitis is one of the world's most common chronic human diseases and has a
significant impact on oral health. Recent evidence has revealed a link between periodontitis …

Saliva biomarkers in oral disease

Y Zhou, Z Liu - Clinica Chimica Acta, 2023 - Elsevier
Saliva is a versatile biofluid that contains a wide variety of biomarkers reflecting both
physiologic and pathophysiologic states. Saliva collection is noninvasive and highly …

Analysis of Salivary Levels of IL-1β, IL17A, OPG and RANK-L in Periodontitis Using the 2017 Classification of Periodontal Diseases—An Exploratory Observational …

M Relvas, R Silvestre, M Gonçalves, C Cabral… - Journal of clinical …, 2023 - mdpi.com
Periodontitis is a chronic disease with a high overall prevalence. It involves a complex
interplay between the immune-inflammatory pathways and biofilm changes, leading to …

Active MMP-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis

M Hernández, M Baeza, IT Räisänen, J Contreras… - Diagnostics, 2021 - mdpi.com
Periodontitis is a host-mediated bacterial disease that affects the tooth attachment
apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical …