Modulators of protein–protein interactions

LG Milroy, TN Grossmann, S Hennig… - Chemical …, 2014 - ACS Publications
Since Hedin's characterization of trypsin and antitrypsin in 1906,(1) arguably the first
account of a regulatory protein–protein interaction (PPI), contemporary understanding of …

Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery

F Majolo, LKOB Delwing, DJ Marmitt… - Phytochemistry …, 2019 - Elsevier
Cancer is one of the largest causes of morbimortality in the world and due to its prevalence
the discovery of novel anticancer drugs in of great importance. The past century brought …

Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus

LS Weyrich, S Duchene, J Soubrier, L Arriola, B Llamas… - Nature, 2017 - nature.com
Recent genomic data have revealed multiple interactions between Neanderthals and
modern humans, but there is currently little genetic evidence regarding Neanderthal …

Demystifying traditional herbal medicine with modern approach

FS Li, JK Weng - Nature plants, 2017 - nature.com
Plants have long been recognized for their therapeutic properties. For centuries, indigenous
cultures around the world have used traditional herbal medicine to treat a myriad of …

On the antiquity of language: the reinterpretation of Neandertal linguistic capacities and its consequences

D Dediu, SC Levinson - Frontiers in psychology, 2013 - frontiersin.org
It is usually assumed that modern language is a recent phenomenon, coinciding with the
emergence of modern humans themselves. Many assume as well that this is the result of a …

The importance of dietary carbohydrate in human evolution

K Hardy, J Brand-Miller, KD Brown… - … Quarterly review of …, 2015 - journals.uchicago.edu
We propose that plant foods containing high quantities of starch were essential for the
evolution of the human phenotype during the Pleistocene. Although previous studies have …

A new era in palaeomicrobiology: prospects for ancient dental calculus as a long-term record of the human oral microbiome

C Warinner, C Speller… - … Transactions of the …, 2015 - royalsocietypublishing.org
The field of palaeomicrobiology is dramatically expanding thanks to recent advances in high-
throughput biomolecular sequencing, which allows unprecedented access to the …

A Neandertal dietary conundrum: Insights provided by tooth enamel Zn isotopes from Gabasa, Spain

K Jaouen, V Villalba-Mouco… - Proceedings of the …, 2022 - National Acad Sciences
The characterization of Neandertals' diets has mostly relied on nitrogen isotope analyses of
bone and tooth collagen. However, few nitrogen isotope data have been recovered from …

The evolution of the human trophic level during the Pleistocene

M Ben‐Dor, R Sirtoli, R Barkai - American journal of physical …, 2021 - Wiley Online Library
The human trophic level (HTL) during the Pleistocene and its degree of variability serve,
explicitly or tacitly, as the basis of many explanations for human evolution, behavior, and …

[图书][B] Cultural anthropology: The human challenge

WA Haviland, HEL Prins, B McBride, D Walrath - 2017 - academia.edu
It is a challenge to make sense of who we are. Where did we come from? Why are we so
radically different from other animals and so surprisingly similar to others? Why do our …