SNARE-complexes drive the fusion of membrane-bound vesicles with target membranes or
with each other (homotypic fusion). The SNARE-proteins are subdivided into Q a, Q b, Q c …

Myosin phosphatase (MP) holoenzyme is a Ser/Thr specific enzyme, which is the member of
protein phosphatase type 1 (PP1) family and composed of a PP1 catalytic subunit …

Schizophrenia (SCZ) is a severe psychiatric disorder characterized by positive symptoms,
negative symptoms, and cognitive deficits. Current antipsychotic treatment in SCZ improves …

Mast cells play pivotal roles in innate and adaptive immunities but are also culprits in allergy,
autoimmunity, and cardiovascular diseases. Mast cells respond to environmental changes …

Vascular dementia (VD) is the most common form of dementia in elderly people. However,
little is understood about the role of microRNAs (miRNAs) involved in cognitive impairment …

Objectives The excessive release of the antidiuretic hormone vasopressin is implicated in
many diseases including cardiovascular disease, diabetes, obesity, and metabolic …

Depolarization of presynaptic terminals stimulates calcium influx, which evokes
neurotransmitter release and activates phosphorylation-based signalling. Here, we present …

Protein phosphatases, by counteracting protein kinases, regulate the reversible
phosphorylation of many substrates involved in synaptic plasticity, a cellular model for …

Abstract SNARE (Soluble NSF (N-ethylmaleimide-sensitive factor) Attachment Receptor)
complex is a trimeric supramolecular organization of SNAP25, syntaxin, and VAMP which …

At the neuromuscular junction (NMJ), motor neurons and myocytes maintain a bidirectional
communication that guarantees adequate functionality. Thus, motor neurons' firing pattern …