Three decades of ultrasound contrast agents: a review of the past, present and future improvements

P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …

[HTML][HTML] Ultrasound contrast agent modeling: a review

M Versluis, E Stride, G Lajoinie, B Dollet… - Ultrasound in medicine & …, 2020 - Elsevier
Ultrasound is extensively used in medical imaging, being safe and inexpensive and
operating in real time. Its scope of applications has been widely broadened by the use of …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Microbubble agents: New directions

E Stride, T Segers, G Lajoinie, S Cherkaoui… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble ultrasound contrast agents have now been in use for several decades and their
safety and efficacy in a wide range of diagnostic applications have been well established …

Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound

S Schoen Jr, MS Kilinc, H Lee, Y Guo… - Advanced drug delivery …, 2022 - Elsevier
Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Imaging methods for ultrasound contrast agents

MA Averkiou, MF Bruce, JE Powers, PS Sheeran… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble contrast agents were introduced more than 25 years ago with the objective of
enhancing blood echoes and enabling diagnostic ultrasound to image the microcirculation …

[HTML][HTML] State-of-the-art of microbubble-assisted blood-brain barrier disruption

KH Song, BK Harvey, MA Borden - Theranostics, 2018 - ncbi.nlm.nih.gov
Focused ultrasound with microbubbles promises unprecedented advantages for blood-brain
barrier disruption over existing intracranial drug delivery methods, as well as a significant …

Molecular ultrasound imaging: current status and future directions

N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …