Unveiling the Veil of RNA Binding Protein Phase Separation in Cancer Biology and Therapy

Y Lin, J Zheng, Z Mai, P Lin, Y Lu, L Cui, X Zhao - Cancer Letters, 2024 - Elsevier
RNA-binding protein (RBP) phase separation in oncology reveals a complex interplay
crucial for understanding tumor biology and developing novel therapeutic strategies …

Crosstalk between circular RNAs and the STAT3 signaling pathway in human cancer

M Almouh, C Soukkarieh, M Kassouha… - Biochimica et Biophysica …, 2024 - Elsevier
Circular RNAs (circRNAs) are endogenous covalently closed single-stranded RNAs
produced by reverse splicing of pre-mRNA. Emerging evidence suggests that circRNAs …

[HTML][HTML] Arid5a uses disordered extensions of its core ARID domain for distinct DNA-and RNA-recognition and gene regulation

J von Ehr, L Oberstrass, E Yazgan… - Journal of Biological …, 2024 - Elsevier
AT-rich interacting domain (ARID)-containing proteins, Arids, are a heterogeneous DNA-
binding protein family involved in transcription regulation and chromatin processing. For the …

bayesReact: Expression-coupled regulatory motif analysis detects microRNA activity in cancer and at the single cell level

AM Rasmussen, A Bouchard-Cote, JS Pedersen - BioRxiv, 2024 - biorxiv.org
Motivation: Regulatory constraints are crucial in maintaining tissue and cell integrity, and
play important roles during developmental processes and environmental responses. Yet …