Elicitation, an effective strategy for the biotechnological production of bioactive high-added value compounds in plant cell factories

K Ramirez-Estrada, H Vidal-Limon, D Hidalgo… - Molecules, 2016 - mdpi.com
Plant in vitro cultures represent an attractive and cost-effective alternative to classical
approaches to plant secondary metabolite (PSM) production (the “Plant Cell Factory” …

Plant growth regulator mediated consequences of secondary metabolites in medicinal plants

K Jamwal, S Bhattacharya, S Puri - … of applied research on medicinal and …, 2018 - Elsevier
Secondary metabolites not only play vital role in plant defense against herbivory and other
interspecies defenses but also used by humans as medicines, flavorings, pharmaceuticals …

Vanadium, recent advancements and research prospects: A review

M Imtiaz, MS Rizwan, S Xiong, H Li, M Ashraf… - Environment …, 2015 - Elsevier
Metal pollution is an important issue worldwide, with various documented cases of metal
toxicity in mining areas, industries, coal power plants and agriculture sector. Heavy metal …

Microwave assisted extraction of secondary metabolites from plants: Current status and future directions

HF Zhang, XH Yang, Y Wang - Trends in Food Science & Technology, 2011 - Elsevier
Plant secondary metabolites are known to be an important source of foods, fragrances,
pigment, drugs and so on. Extraction is one of the crucial steps for research and …

Production of the anticancer drug taxol in Taxus baccata suspension cultures: a review

S Malik, RM Cusidó, MH Mirjalili, E Moyano… - Process …, 2011 - Elsevier
Plant cell factories constitute an alternative source of high added value phytochemicals such
as the anticancer drug taxol (generic name paclitaxel), biosynthesized in Taxus spp. The …

Research progress on the source, production, and anti-cancer mechanisms of paclitaxel

Y Yan-Hua, MAO Jia-Wang, TAN Xiao-Li - Chinese Journal of Natural …, 2020 - Elsevier
Paclitaxel, a tetracyclic diterpenoid compounds, was firstly isolated from the bark of the
Pacific yew trees. Currently, as a low toxicity, high efficiency, and broad-spectrum natural …

Endophytic fungi: novel sources of anticancer lead molecules

S Chandra - Applied microbiology and biotechnology, 2012 - Springer
Cancer is a major killer disease all over the world and more than six million new cases are
reported every year. Nature is an attractive source of new therapeutic compounds, as a …

A review: recent advances and future prospects of taxol-producing endophytic fungi

X Zhou, H Zhu, L Liu, J Lin, K Tang - Applied microbiology and …, 2010 - Springer
In the urgent search for more effective ways to treat cancer, new extraction methods of taxol
from endophytic fungus have demonstrated high potential in increasing the efficiency of …

Synergistic antiviral effects against SARS-CoV-2 by plant-based molecules

A Prasad, M Muthamilarasan, M Prasad - Plant Cell Reports, 2020 - Springer
The exponential spread of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emphasizes the immediate need for effective antiviral drugs and vaccines that could control …

Endophytes: exploiting biodiversity for the improvement of natural product-based drug discovery

A Staniek, HJ Woerdenbag… - Journal of plant interactions, 2008 - Taylor & Francis
Endophytes, microorganisms that colonize internal tissues of all plant species, create a huge
biodiversity with yet unknown novel natural products, presumed to push forward the frontiers …