Inflammasomes Are Influenced by Epigenetic and Autophagy Mechanisms in Colorectal Cancer Signaling

G Műzes, F Sipos - International Journal of Molecular Sciences, 2024 - mdpi.com
Inflammasomes contribute to colorectal cancer signaling by primarily inducing inflammation
in the surrounding tumor microenvironment. Its role in inflammation is receiving increasing …

miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in …

Y Liu, XK Meng, W Shao, Y Liu, C Tang, S Deng… - Neurochemical …, 2024 - Springer
Reduced myelin stability observed in the early stages of Alzheimer's disease leads to spatial
learning and memory impairment. Exercise has been shown to protect nerves, reduce the …

[HTML][HTML] A Narrative Literature Review on Sepsis: A Primary Manifestation of Colorectal Neoplasm

L Masood, A Müller, NZ Ali, A Mummadisetty, A Yahya… - Cureus, 2023 - ncbi.nlm.nih.gov
Sepsis and colorectal cancer (CRC) exhibit a complex relationship that warrants further
exploration. This review delves into the interplay of factors between sepsis and CRC …

[HTML][HTML] FAN1 Deletion Variant in Basenji Dogs with Fanconi Syndrome

FHG Farias, T Mhlanga-Mutangadura, J Guo, L Hansen… - Genes, 2024 - mdpi.com
Background: Fanconi syndrome is a disorder of renal proximal tubule transport
characterized by metabolic acidosis, amino aciduria, glucosuria, and phosphaturia. There …

Investigating the effects of the ARG258HIS mutation on RAD51C in inherited Fanconi Anemia and cancer disease

S Seifeldin, M Saeed, K Alshaghdali… - Journal of …, 2024 - Taylor & Francis
Fanconi anemia is a rare chromosomal instability disorder associated with developmental
abnormalities, bone marrow failure, and a heightened susceptibility to leukemia and other …

Mutation spectrum, expression profiling, and prognosis evaluation of Fanconi anemia signaling pathway genes for 4259 patients with myelodysplastic syndromes or …

L Chang, L Zhang, B Zhao, X Cheng, Y Wan… - BMC Medical …, 2023 - Springer
Abstract Background Individuals diagnosed with Fanconi anemia (FA), an uncommon
disorder characterized by chromosomal instability affecting the FA signaling pathway, exhibit …

Phenotypic and genotypic correlation evaluation of 148 pediatric patients with Fanconi anemia in a Chinese rare disease cohort

L Chang, L Zhang, W An, Y Wan, Y Cai, Y Lan… - Clinica Chimica …, 2023 - Elsevier
Background Fanconi anemia (FA) is a rare autosomal recessive, X-linked or autosomal
dominant disease. Few large-scale FA investigations of rare disease cohorts have been …

P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA

W Xu, K Deng, L Pei - Biochemical Pharmacology, 2025 - Elsevier
Colorectal cancer (CRC) is a malignancy with high global incidence and mortality rates,
posing a serious threat to human health. Despite favorable outcomes following early …

Fanconi Anemia in a 31-Year-Old Patient with Multiple Malignant Tumor Foci, Including Appendiceal Cancer, and Multiple Coexisting Pathologies

M Dyaczyński, L Sannikova… - The American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Patient: Male, 31-year-old Final Diagnosis: Appendiceal cancer• mucinous type• grade G3
Symptoms: High levels of carcinoembryonic antigen (CEA) Clinical Procedure …

Specific binding of Hg2+ to mismatched base pairs involving 5-hydroxyuracil in duplex DNA

H Torigoe, J Kondo, F Arakawa - Journal of Inorganic Biochemistry, 2023 - Elsevier
Metal ion–nucleic acid interactions contribute significantly to nucleic acid structure and
biological activity and have potential applications in nanotechnology. Hg 2+ specifically …