Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Serpins are a superfamily of proteins characterized by their common function as serine
protease inhibitors. So far, 36 serpins from nine clades have been identified. These proteins …

Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …

Retinal and choroidal neovascularization are a major cause of significant visual impairment,
worldwide. Understanding the various factors involved in the accompanying …

Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Diabetic retinopathy (DR) is the leading cause of blindness in the working-age population in
developed countries, and its prevalence will increase as the global incidence of diabetes …

Age-related macular degeneration (AMD) is the leading cause of vision loss in geriatric
population. Intravitreal (IVT) injections are popular clinical option. Biologics and small …

Strong epidemiological and experimental evidence indicate that both age and hypertension
lead to significant functional and structural impairment of the cerebral microcirculation …

Background Several common retinal diseases that cause blindness are characterised by
pathological neovascularisation accompanied by inflammation and neurodegeneration …