Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

In mammalian cells, phospholipids and cholesterol are assembled into bilayer membranes
forming the plasma membrane, nuclear envelope, mitochondria, endoplasmic reticulum …

Background The mitochondrial (mt) genome has been used as an effective tool for
phylogenetic and population genetic analyses in vertebrates. However, the structure and …

Genome sequencing has resulted in the identification of a large number of uncharacterized
genes with unknown functions. It is widely recognized that determination of the intracellular …

So far some nuclear receptors for bile acids have been identified. However, no cell surface
receptor for bile acids has yet been reported. We found that a novel G protein-coupled …

About 12,000 years ago in the Near East, humans began the transition from hunter-
gathering to agriculture-based societies. Barley was a founder crop in this process, and the …

Viruses of the family Flaviviridae are important pathogens of humans and other animals and
are currently classified into four genera. To better understand their diversity, evolutionary …

The cadmium (Cd) over‐accumulating rice (Oryza sativa) cv Cho‐Ko‐Koku was previously
shown to have an enhanced rate of root‐to‐shoot Cd translocation. This trait is controlled by …

Background Membrane proteins form key nodes in mediating the cell's interaction with the
surroundings, which is one of the main reasons why the majority of drug targets are …

Motivation: A variety of tools are available to predict the topology of transmembrane proteins.
To date no independent evaluation of the performance of these tools has been published. A …