Mechanism of action of trazodone: a multifunctional drug

SM Stahl - CNS spectrums, 2009 - cambridge.org
Multifunctional drugs are those with more than one therapeutic mechanism. Trazodone is a
multifunctional drug with dose-dependent pharmacologic actions. That is, it has hypnotic …

Pharmacological analysis of male rat sexual behavior

D Bitran, EM Hull - Neuroscience & Biobehavioral Reviews, 1987 - Elsevier
Pharmacological influences on male rat sexual behavior are reviewed in an attempt to
identify neurotransmitters and their respective receptor types that regulate various factors …

[图书][B] Incentive relativity

CF Flaherty - 1999 - books.google.com
Incentive Relativity summarizes the early history of research on the effects of reward
magnitude on animal behaviour, emphasizing those studies that led to recognition that …

Electrophysiological responses of serotoninergic dorsal raphe neurons to 5‐HT1A and 5‐HT1B agonists

JS Sprouse, GK Aghajanian - Synapse, 1987 - Wiley Online Library
A direct comparison was made of the effects of serotonin 5‐HT1A and 5‐HT1B selective
compounds on the spontaneous firing rate of dorsal raphe serotoninergic neurons in chloral …

Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro.

R Andrade, RA Nicoll - The Journal of physiology, 1987 - Wiley Online Library
1. The actions of serotonin (5‐HT) on pyramidal cells of the CA1 region of the rat
hippocampus were characterized using intracellular recording in in vitro brain slices. 2. 5 …

Serotonin function in anxiety: II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects

DS Charney, SW Woods, WK Goodman… - …, 1987 - Springer
To assess the role of serotonin function in the development of panic anxiety, the behavioral
and biochemical responses to the serotonin receptor agonist, m-chlorophenylpiperazine …

The role of serotonin in schizophrenia

A Bleich, SL Brown, R Kahn… - Schizophrenia …, 1988 - academic.oup.com
Abstract Studies examining serotonin (5-hydroxytryptamine; 5HT) in schizophrenia show
variable and inconsistent findings, which might reflect the heterogeneity of the disease …

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H] 5-HT,[3H] 8-OH-DPAT,(−)[125I] …

D Hoyer, G Engel, HO Kalkman - European journal of pharmacology, 1985 - Elsevier
The pharmacological characteristics of the binding of [3 H] 8-OH-DPAT ([3 H] 8-hydroxy-2 (di-
n-propylamino) tetralin,[125 I] CYP ((−)[125 I] iodocyanopindolol)(in the presence of 30 μM …

Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology

J Zohar, TR Insel - Biological psychiatry, 1987 - Elsevier
The diagnosis, treatment, and pathophysiology of obsessive-compulsive disorder (OCD)
were examined in a series of studies utilizing psychobiological approaches. Putative …

Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: a comparative study with dorsal raphe neurons

JS Sprouse, GK Aghajanian - Neuropharmacology, 1988 - Elsevier
In low cerveau isolé transected rats, the effects of microiontophoretic application of putative
serotonin 5-HT 1A and 5-HT 1B agonists on the spontaneous firing rate of CA 1 pyramidal …