Current molecular and clinical insights into uveal melanoma
M Fallico, G Raciti, A Longo… - International …, 2021 - spandidos-publications.com
Uveal melanoma (UM) represents the most prominent primary eye cancer in adults. With an
incidence of approximately 5 cases per million individuals annually in the United States, UM …
incidence of approximately 5 cases per million individuals annually in the United States, UM …
The diverse roles of SPOP in prostate cancer and kidney cancer
Multiple studies have confirmed that speckle-type pox virus and zinc finger (POZ) protein
(SPOP) functions as a substrate adaptor of cullin 3-based E3 ligase and has a crucial role in …
(SPOP) functions as a substrate adaptor of cullin 3-based E3 ligase and has a crucial role in …
The crucial role of epigenetic regulation in breast cancer anti-estrogen resistance: Current findings and future perspectives
OA Sukocheva, E Lukina, M Friedemann… - Seminars in cancer …, 2022 - Elsevier
Breast cancer (BC) cell de-sensitization to Tamoxifen (TAM) or other selective estrogen
receptor (ER) modulators (SERM) is a complex process associated with BC heterogeneity …
receptor (ER) modulators (SERM) is a complex process associated with BC heterogeneity …
DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression
IV Pronina, VI Loginov, AM Burdennyy, MV Fridman… - Gene, 2017 - Elsevier
The methylation of promoter CpG islands and the interaction between microRNAs (miRNAs)
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …
and messenger RNAs (mRNAs) of target genes are considered two crucial mechanisms for …
Genetics and RNA regulation of uveal melanoma
Simple Summary Uveal melanoma (UM) is a rare eye cancer with a high mortality rate due
to metastases, leading to death in up to 50% of patients within 10 years from UM diagnosis …
to metastases, leading to death in up to 50% of patients within 10 years from UM diagnosis …
MicroRNA regulation of epigenetic modifiers in breast cancer
Epigenetics refers to the heritable changes in gene expression without a change in the DNA
sequence itself. Two of these major changes include aberrant DNA methylation as well as …
sequence itself. Two of these major changes include aberrant DNA methylation as well as …
Recent approaches for the treatment of uveal melanoma: Opportunities and challenges
SA Khan, WH Almalki, S Arora, P Kesharwani - Critical reviews in oncology …, 2024 - Elsevier
Uveal melanoma (UM) is the most prevalent primary intraocular cancer in adult population.
Primary methods for treatment of UM involves surgery Proton Beam Therapy (PBT), Plaque …
Primary methods for treatment of UM involves surgery Proton Beam Therapy (PBT), Plaque …
MicroRNAs as a clue to overcome breast cancer treatment resistance
I Garrido-Cano, B Pattanayak, A Adam-Artigues… - Cancer and Metastasis …, 2022 - Springer
Breast cancer is the most frequent cancer in women worldwide. Despite the improvement in
diagnosis and treatments, the rates of cancer relapse and resistance to therapies remain …
diagnosis and treatments, the rates of cancer relapse and resistance to therapies remain …
Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism
J Dong, D Xiao, Z Zhao, P Ren, C Li, Y Hu, J Shi, H Su… - Oncogenesis, 2017 - nature.com
Tumor cells must activate specific transporters to meet their increased glutamine metabolic
demands. Relative to other glutamine transporters, the ASC family transporter 2 (ASCT2 …
demands. Relative to other glutamine transporters, the ASC family transporter 2 (ASCT2 …
Androgen receptor signaling inhibition in advanced castration resistance prostate cancer: what is expected for the near future?
Simple Summary Prostate cancer progression is mainly driven by the androgen receptor
(AR) signaling pathway and its inhibition has been the cornerstone in the treatment of …
(AR) signaling pathway and its inhibition has been the cornerstone in the treatment of …