Ontogeny of adult neural stem cells in the mammalian brain
Neural stem cells (NSCs) persist into adulthood in the subgranular zone (SGZ) of the
dentate gyrus in the hippocampus and in the ventricular-subventricular zone (V-SVZ) of the …
dentate gyrus in the hippocampus and in the ventricular-subventricular zone (V-SVZ) of the …
Drugs and endogenous factors as protagonists in neurogenic stimulation
RA Chiareli, BL Marques, GA de Carvalho… - Stem Cell Reviews and …, 2022 - Springer
Neurogenesis is a biological process characterized by new neurons formation from stem
cells. For decades, it was believed that neurons only multiplied during development and in …
cells. For decades, it was believed that neurons only multiplied during development and in …
Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer's disease
MY Kim, MJ Kim, C Lee, J Lee, SS Kim… - … & Molecular Medicine, 2023 - nature.com
Enhancing adult neurogenesis in the brain has been suggested as a potential therapeutic
strategy for AD. We developed a screening platform, ATRIVIEW®, for molecules that activate …
strategy for AD. We developed a screening platform, ATRIVIEW®, for molecules that activate …
Cholesterol and hedgehog signaling: mutual regulation and beyond
S Xu, C Tang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The Hedgehog (HH) signaling is one of the key agents that govern the precisely regulated
developmental processes of multicellular organisms in vertebrates and invertebrates. The …
developmental processes of multicellular organisms in vertebrates and invertebrates. The …
Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity …
Sonic hedgehog (SHH) signaling is essential for the differentiation and migration of early
stem cell populations during cerebellar development. Dysregulation of SHH-signaling can …
stem cell populations during cerebellar development. Dysregulation of SHH-signaling can …
[PDF][PDF] Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer's disease
Enhancing adult neurogenesis in the brain has been suggested as a potential therapeutic
for AD. We developed a screening platform ATRIVIEW® for molecules activating neuronal …
for AD. We developed a screening platform ATRIVIEW® for molecules activating neuronal …
[图书][B] Defining How Developmental Cadmium Exposure Female-Specifically Induces Adult Metabolic Disease
TW Jackson - 2021 - search.proquest.com
Responses to many environmental toxicants and genetic mutations are sexually dimorphic.
The mechanisms underlying sex-specific phenotypic responses are varied and depend on …
The mechanisms underlying sex-specific phenotypic responses are varied and depend on …