The rapid development of drug nanocarriers has benefited from the surface hydrophilic
polymers of particles, which has improved the pharmacokinetics of the drugs. Polyethylene …

Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …

Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid
nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of …

Oligonucleotides (ONs) comprise a rapidly growing class of therapeutics. In recent years, the
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …

Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …