Xanthones, a promising anti-inflammatory scaffold: Structure, activity, and drug likeness analysis

Z Feng, X Lu, L Gan, Q Zhang, L Lin - Molecules, 2020 - mdpi.com
Inflammation is the body's self-protective response to multiple stimulus, from external
harmful substances to internal danger signals released after trauma or cell dysfunction …

Xanthones and anthranoids from the medicinal plants of Africa

O Mazimba, F Nana, V Kuete, GS Singh - Medicinal plant research in Africa, 2013 - Elsevier
Xanthones or xanthen-9H-ones (dibenzo-gamma-pirone) comprise an important class of
oxygenated heterocycles whose role is well known in medicinal chemistry. The biological …

Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies

KY Khaw, SB Choi, SC Tan, HA Wahab, KL Chan… - Phytomedicine, 2014 - Elsevier
Garcinia mangostana is a well-known tropical plant found mostly in South East Asia. The
present study investigated acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) …

[HTML][HTML] 1, 3, 5, 6-Tetrahydroxyxanthone, a natural xanthone, induces diuresis and saluresis in normotensive and hypertensive rats

LNB Mariano, T Boeing, V Cechinel-Filho… - Chemico-Biological …, 2019 - Elsevier
The aim of the present study was to evaluate the diuretic effect of 1, 3, 5, 6-
tetrahydroxyxanthone (THX), isolated from preparations of Garcinia achachairu Rusby …

Antibacterial dihydrobenzopyran and xanthone derivatives from Garcinia cowa stem barks

I Siridechakorn, W Phakhodee, T Ritthiwigrom… - Fitoterapia, 2012 - Elsevier
Two new compounds, garciniacowol (1) and garciniacowone (2) along with 15 known
compounds were isolated from the stem barks of Garcinia cowa. Their structures were …

[HTML][HTML] Xanthones from the leaves of Garcinia cowa induce cell cycle arrest, apoptosis, and autophagy in cancer cells

Z Xia, H Zhang, D Xu, Y Lao, W Fu, H Tan, P Cao… - Molecules, 2015 - mdpi.com
Two new xanthones, cowaxanthones G (1) and H (2), and 23 known analogues were
isolated from an acetone extract of the leaves of Garcinia cowa. The isolated compounds …

Antibacterial Activity of Eight Medicinal Plants from the Traditional Pharmacopoeia of Niger

MII Abdoulahi, MD Yanick Kevin… - Journal of Tropical …, 2023 - Wiley Online Library
The emergence of multidrug bacterial resistance poses a great public health problem and
requires a constant search for new antibacterial agents. However, Niger's flora possesses …

Xanthones inhibitors of α-glucosidase and glycation from Garcinia nobilis

H Fouotsa, AM Lannang, CD Mbazoa, S Rasheed… - Phytochemistry …, 2012 - Elsevier
One new xanthone, caroxanthone (1) together with six known xanthones, 4-prenyl-2-(3, 7-
dimethyl-2, 6-octadienyl)-1, 3, 5, 8-tetrahydroxyxanthone (2), smeathxanthone A (3) …

Dual/multitargeted xanthone derivatives for Alzheimer's disease: where do we stand?

MI Cruz, H Cidade, M Pinto - Future Medicinal Chemistry, 2017 - Taylor & Francis
To date, the current therapy for Alzheimer's disease (AD) based on acetylcholinesterase
inhibitors is only symptomatic, being its efficacy limited. Hence, the recent research has …

Antibacterial and antioxidant activities of compounds isolated from the leaves of Symphonia globulifera (Clusiaceae) and their chemophenetic significance

DG Téné, AE Tih, MHK Kamdem, RM Talla… - Biochemical Systematics …, 2021 - Elsevier
The phytochemical study was done on the methanol extract from of the leaves of Symphonia
globulifera. This plant has been used in traditional medicine to treat of different ailments …