One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

Abstract In 1970 the Boulder Committee described the basic principles of the development
of the CNS, derived from observations on the human embryonic cerebrum. Since then …

The complexity of the human brain has made it difficult to study many brain disorders in
model organisms, highlighting the need for an in vitro model of human brain development …

For over three decades, Allan N. Schore has authored numerous volumes, chapters, and
articles on regulation theory, a biopsychosocial model of the development …

Many structural features of the mammalian central nervous system can be explained by a
morphogenetic mechanism that involves mechanical tension along axons, dendrites and …

The cerebral neocortex is segregated into six horizontal layers, each containing unique
populations of molecularly and functionally distinct excitatory projection (pyramidal) neurons …

During corticogenesis, early-born neurons of the preplate and layer 6 are important for
guiding subsequent neuronal migrations and axonal projections. Tbr1 is a putative …

The functioning of the nervous system depends upon the underlying detailed and highly
stereotyped patterns of neuronal connectivity. How these precise patterns of synaptic …

During the second and third trimesters of human gestation, rapid neurodevelopment is
underpinned by fundamental processes including neuronal migration, cellular organization …

Conscious perception in mammals depends on precise circuit connectivity between cerebral
cortex and thalamus; the evolution and development of these structures are closely linked …