Penetration of drugs through skin, a complex rate-controlling membrane

MA Bolzinger, S Briançon, J Pelletier… - Current opinion in colloid …, 2012 - Elsevier
Penetration of molecules and particles inside and through skin has long been well
documented but it now merits renewed attention as a result of new areas of concern such as …

Caffeine's mechanisms of action and its cosmetic use

A Herman, AP Herman - Skin pharmacology and physiology, 2012 - karger.com
Caffeine is being increasingly used in cosmetics due to its high biological activity and ability
to penetrate the skin barrier. This alkaloid is frequently used as a hydrophilic model …

Recent advances in follicular drug delivery of nanoparticles

A Patzelt, J Lademann - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: The improvement of percutaneous absorption represents a clear
dermatopharmaceutical aim. Recently, the hair follicle was recognized to be an important …

Hyaluronic acid and HA-modified cationic liposomes for promoting skin penetration and retention

C Ni, Z Zhang, Y Wang, Z Zhang, X Guo, H Lv - Journal of Controlled …, 2023 - Elsevier
Hyaluronic acid (HA) has been widely used in cosmetics and topical preparations owing to
its favorable moisturizing property and potential in enhancing drugs' skin permeability. Here …

Anti-obesity effect of a novel caffeine-loaded dissolving microneedle patch in high-fat diet-induced obese C57BL/6J mice

M Dangol, S Kim, CG Li, SF Lahiji, M Jang, Y Ma… - Journal of controlled …, 2017 - Elsevier
Natural products such as caffeine have been found to be effective in reducing body weight
through lipolysis. Here, we report the successful loading of caffeine onto dissolving …

Electrospun cellulose acetate/polyvinylpyrrolidone fiber mats as potential cosmetic under-eye masks for caffeine delivery

P Tipduangta, W Watcharathirawongs… - Journal of Drug Delivery …, 2023 - Elsevier
Cosmetic products for skin aging including infraorbital dark circles are getting popular.
Caffeine incorporation into beauty skin masks is beneficial for this concern but the topical …

Design of dialdehyde cellulose crosslinked poly (vinyl alcohol) hydrogels for transdermal drug delivery and wound dressings

M Muchová, L Münster, Z Capáková… - Materials Science and …, 2020 - Elsevier
Dialdehyde cellulose (DAC) was used as an efficient and low-toxicity crosslinker to prepare
thin PVA/DAC hydrogel films designed for topical applications such as drug-loaded patches …

Anti-obesity effects of chlorogenic acid and caffeine-lipid nanoparticles through PPAR-γ/C/EBP-ɑ pathways

B Uner, MS Macit Celebi - International Journal of Obesity, 2023 - nature.com
Obesity is considered one of the most crucial health problems of the century. Therefore,
reducing obesity is critically important. Caffeine (CF) and chlorogenic acid (CLA), which are …

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

X Liu, JE Grice, J Lademann, N Otberg… - British journal of …, 2011 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Depending on the body site and the
substances, the hair follicles can contribute significantly to the penetration of topically …

Confocal Raman microscopy and multivariate statistical analysis for determination of different penetration abilities of caffeine and propylene glycol applied …

SM Ascencio, CS Choe, MC Meinke, RH Müller… - European journal of …, 2016 - Elsevier
Propylene glycol is one of the known substances added in cosmetic formulations as a
penetration enhancer. Recently, nanocrystals have been employed also to increase the skin …