Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors
for decades with the advantages of excellent biodegradability, biocompatibility, and high …

Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …

Extracellular vesicles (EVs) are increasingly being recognized as candidate drug delivery
systems due to their ability to functionally transfer biological cargo between cells. However …

Using a family of cationic gold nanoparticles (NPs) with similar size and charge, we
demonstrate that proper surface engineering can control the nature and identity of protein …

The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …

Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

Nonviral vectors which offer a safer and versatile alternative to viral vectors have been
developed to overcome problems caused by viral carriers. However, their transfection …

There is growing interest in PEGylation of cationic polymeric vehicles for gene delivery in
order to improve vehicle stability and reduce toxicity, but little is known about the effects of …

Although surgical resection provides a straightforward and effective treatment for most
malignant solid tumors, tumor recurrence and acute postoperative pain continue to be two …

Gene therapy is a promising approach for personalized medicine, but its application in
humans requires development of efficient and safe vehicles. PEGylated liposomes are some …