Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

Glycan is an essential cell component that usually exists in either a free form or a
glycoconjugated form. Glycosylation affects the regulatory function of glycoconjugates in …

Quantification, characterization and biofunctional studies of N-glycans on proteins remain
challenging tasks due to the complexity, diversity and low abundance of these glycans. The …

Structurally well-defined IgG-Fc glycoforms are highly demanded for understanding the
effects of glycosylation on an antibody's effector functions. We report in this paper …

Chemoenzymatic synthesis is emerging as a promising approach to the synthesis of
homogeneous glycopeptides and glycoproteins highly demanded for functional glycomics …

The structural diversity of glycoproteins often comes from post-translational glycosylation
with heterogeneous N-glycans. Understanding the complexity of glycans related to various …

N‐Glycosylation, a main post‐translational modification of Immunoglobulin G (IgG), plays a
significant role in modulating the immune functions of IgG. However, the precise function …

Automated glycan assembly (AGA) aims at accelerating access to synthetic
oligosaccharides to meet the demand for defined glycans as tools for molecular …

Comprehensive Summary Naturally occurring interleukin‐2 (IL‐2) is a pleiotropic
glycoprotein that regulates immune responses by controlling the differentiation and …

The presence of NHAc groups in the substrates (both glycosyl donors and acceptors)
significantly reduced the reactivity of glycosylation. This decrease was attributed to the NHAc …