The outcome of a glycosylation reaction critically depends on the reactivity of all reaction
partners involved: the donor glycoside (the electrophile), the activator (that generally …

The search for stereoselective glycosylation reactions has occupied synthetic carbohydrate
chemists for decades. Traditionally, most attention has been focused on controlling the SN2 …

Mechanism of chemical O-glycosylation : from early studies to recent discoveries - Organic &
Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B916088D Royal Society of Chemistry …

A set of model nucleophiles of gradually changing nucleophilicity is used to probe the
glycosylation reaction mechanism. Glycosylations of ethanol-based acceptors, bearing …

Visible‐light irradiation of 4‐p‐methoxyphenyl‐3‐butenylthioglucoside donors in the
presence of Umemoto's reagent and alcohol acceptors serves as a mild approach to O …

O-GalNAc glycans (or mucin O-glycans) play pivotal roles in diverse biological and
pathological processes, including tumor growth and progression. Structurally defined O …

Herein, we report a highly efficient total synthesis of Staphylococcus aureus type 8
trisaccharide repeating unit in a lesser number of steps and high stereoselectivity. The …

This Perspective outlines work in the Crich group on the diastereoselective synthesis of the
so-called difficult classes of glycosidic bond: the 2-deoxy-β-glycopyranosides, the β …

The first automated solution-phase synthesis of β-1, 4-mannuronate and β-1, 4-mannan
oligomers has been accomplished by using a β-directing C-5 carboxylate strategy. By …

The sequence, length and substitution of a polysaccharide influence its physical and
biological properties. Thus, sequence controlled polysaccharides are important targets to …