Three‐dimensional cell culture models, such as spheroids, can be used in the process of the
development of new anticancer agents because they are able to closely mimic the main …

New cancer drug approval rates are≤ 5% despite significant investments in cancer
research, drug discovery and development. One strategy to improve the rate of success of …

Abstract N. sativa (N. sativa) has been used since ancient times, when a scientific concept
about the use of medicinal plants for the treatment of human illnesses and alleviation of their …

Cancer is a serious health problem and the second leading cause of death around the
globe. Present review is an attempt to provide utmost information based on ethno …

Bacterial cellulose (BC) has emerged as a biomaterial for diverse biomedical applications
owing to its unique structural, physico-chemical, mechanical, and biological features. Its …

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are highly expressed in
tumor cells, as well as in organs involved in absorption and secretion processes, mediating …

The present invention provides heterocyclic linker com pounds useful for linking drug
moieties to ligands. The compounds also include drug-ligand conjugates comprising a …

Cystic echinococcosis (CE) is a zoonotic helminthiasis caused by different species of the
genus Echinococcus, and is a major economic and public health concern worldwide …

Background: Haemonchus contortus is an important pathogenic nematode parasite and
major economic constraint of small ruminants in tropics and subtropics regions. This review …

6,268.488 B1 7/2001 Barbas, III et al. Devy et al.,“Plasmin-activated doxorubicin prodrugs
containing a spacer reduce tumor growth and angiogenesis without systemic tox 6,677,435 …