Abstract Caveolin-1 (CAV1) is an oncogenic membrane protein associated with endocytosis,
extracellular matrix organisation, cholesterol distribution, cell migration and signaling …

Abstract Caveolin-1 (CAV1) is commonly considered to function as a cell surface protein, for
instance in the genesis of caveolae. Nonetheless, it is also present in many intracellular …

Gastric cancer (GC) is the fifth most common tumor and the third most deadly cancer
worldwide. N6-methyladenosine (m6A) modification has been reported to play a regulatory …

Breast cancer is one of the most frequently diagnosed cancers and the leading cause of
cancer-related deaths in women worldwide, whereby mortality is largely attributable to the …

Oxidized LDLs (oxLDLs) and oxysterols play a key role in endothelial dysfunction and the
development of atherosclerosis. The loss of vascular endothelium function negatively …

Cellular senescence is a feature of most somatic cells. It is characterized by an irreversible
cell cycle arrest and by the ability to secrete a plethora of mediators of inflammation and …

Close contacts between endoplasmic reticulum and mitochondria enable reciprocal Ca2+
exchange, a key mechanism in the regulation of mitochondrial bioenergetics. During the …

Caveolae, specialized plasma membrane invaginations present in most cell types, play
important roles in multiple cellular processes including cell signaling, lipid uptake and …

Caveolin-1 (CAV1) is a scaffolding protein with a controversial role in cancer. This review
will initially discuss earlier studies focused on the role as a tumor suppressor before …

Abstract Caveolin-1 (CAV1) has long been implicated in cancer progression, and while
widely accepted as an oncogenic protein, CAV1 also has tumor suppressor activity. CAV1 …