Imaging endpoints for clinical trials in MacTel type 2
D Pauleikhoff, L Pauleikhoff, EY Chew - Eye, 2022 - nature.com
Abstract Introduction Macular Telangiectasia type 2 (MacTel) is a bilateral
neurodegenerative disease associated with dysfunction in the serine and lipid metabolism …
neurodegenerative disease associated with dysfunction in the serine and lipid metabolism …
[HTML][HTML] Macular telangiectasia type 2: a classification system using MultiModal imaging MacTel project report number 10
Purpose To develop a severity classification for macular telangiectasia type 2 (MacTel)
disease using multimodal imaging. Design An algorithm was used on data from a …
disease using multimodal imaging. Design An algorithm was used on data from a …
iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function
KT Eade, BRE Ansell, S Giles, R Fallon… - The Journal of …, 2023 - Am Soc Clin Investig
Patient-derived induced pluripotent stem cells (iPSCs) provide a powerful tool for identifying
cellular and molecular mechanisms of disease. Macular telangiectasia type 2 (MacTel) is a …
cellular and molecular mechanisms of disease. Macular telangiectasia type 2 (MacTel) is a …
Spectral domain OCT features in type 2 macular telangiectasia (type 2 MacTel): its relevance with clinical staging and visual acuity
R Venkatesh, NG Reddy, P Mishra, S Agrawal… - International Journal of …, 2022 - Springer
Background To report spectral domain optical coherence tomography (SDOCT) imaging
findings in type 2 macular telangiectasia (MacTel) and correlate them with clinical stages …
findings in type 2 macular telangiectasia (MacTel) and correlate them with clinical stages …
Histology and clinical imaging lifecycle of black pigment in fibrosis secondary to neovascular age-related macular degeneration
L Chen, D Cao, JD Messinger, T Ach, D Ferrara… - Experimental eye …, 2022 - Elsevier
Purpose Melanotic cells with large spherical melanosomes, thought to originate from retinal
pigment epithelium (RPE), are found in eyes with neovascular age-related macular …
pigment epithelium (RPE), are found in eyes with neovascular age-related macular …
Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2
Purpose To investigate the progression characteristics of ellipsoid zone (EZ) loss in eyes
with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements …
with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements …
Progression of vascular changes in macular telangiectasia type 2: comparison between SD-OCT and OCT angiography
D Pauleikhoff, F Gunnemann, M Book… - Graefe's Archive for …, 2019 - Springer
Purpose To investigate the different appearances of vascular changes in macular
telangiectasia type 2 (MacTel) and to describe their possible progression, the vascular …
telangiectasia type 2 (MacTel) and to describe their possible progression, the vascular …
Characterizing retinal–choroidal anastomosis in macular telangiectasia type 2 with optical coherence tomography angiography
Purpose: To characterize structural and angiographic findings in macular telangiectasia
Type 2 (MacTel 2) and examine associations with visual acuity. Methods: MacTel 2 patients …
Type 2 (MacTel 2) and examine associations with visual acuity. Methods: MacTel 2 patients …
Hyperpigmented epiretinal membrane in macular telangiectasia type 2: imaging characteristics and correlation with transretinal pigment migration
D Cabral, P Ramtohul, TR Kaden, S Tenreiro… - Eye, 2023 - nature.com
Objectives To explore the features of black hyperpigmentation in macular telangiectasia
(MacTel) type 2 and correlate these findings with the characteristics of hyperpigmented …
(MacTel) type 2 and correlate these findings with the characteristics of hyperpigmented …
[HTML][HTML] High-throughput ultrastructural analysis of macular telangiectasia type 2
CL Zucker, PS Bernstein, RL Schalek… - Frontiers in …, 2024 - frontiersin.org
Introduction Macular Telangiectasia type 2 (MacTel), is an uncommon form of late-onset,
slowly-progressive macular degeneration. Associated with regional Müller glial cell loss in …
slowly-progressive macular degeneration. Associated with regional Müller glial cell loss in …