Neural recording and modulation technologies

R Chen, A Canales, P Anikeeva - Nature Reviews Materials, 2017 - nature.com
In the mammalian nervous system, billions of neurons connected by quadrillions of
synapses exchange electrical, chemical and mechanical signals. Disruptions to this network …

The role of variability in motor learning

AK Dhawale, MA Smith… - Annual review of …, 2017 - annualreviews.org
Trial-to-trial variability in the execution of movements and motor skills is ubiquitous and
widely considered to be the unwanted consequence of a noisy nervous system. However …

The basal ganglia control the detailed kinematics of learned motor skills

AK Dhawale, SBE Wolff, R Ko, BP Ölveczky - Nature neuroscience, 2021 - nature.com
The basal ganglia are known to influence action selection and modulation of movement
vigor, but whether and how they contribute to specifying the kinematics of learned motor …

[HTML][HTML] Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

S Bowles, J Hickman, X Peng, WR Williamson… - Neuron, 2022 - cell.com
Vagus nerve stimulation (VNS) is a neuromodulation therapy for a broad and expanding set
of neurologic conditions. However, the mechanism through which VNS influences central …

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

G Dölen, A Darvishzadeh, KW Huang, RC Malenka - Nature, 2013 - nature.com
Social behaviours in species as diverse as honey bees and humans promote group survival
but often come at some cost to the individual. Although reinforcement of adaptive social …

[HTML][HTML] Hierarchical motor control in mammals and machines

J Merel, M Botvinick, G Wayne - Nature communications, 2019 - nature.com
Advances in artificial intelligence are stimulating interest in neuroscience. However, most
attention is given to discrete tasks with simple action spaces, such as board games and …

[HTML][HTML] Neural reuse of action perception circuits for language, concepts and communication

F Pulvermüller - Progress in neurobiology, 2018 - Elsevier
Neurocognitive and neurolinguistics theories make explicit statements relating specialized
cognitive and linguistic processes to specific brain loci. These linking hypotheses are in …

Acute off-target effects of neural circuit manipulations

TM Otchy, SBE Wolff, JY Rhee, C Pehlevan, R Kawai… - Nature, 2015 - nature.com
Rapid and reversible manipulations of neural activity in behaving animals are transforming
our understanding of brain function. An important assumption underlying much of this work …

Locomotor primitives in newborn babies and their development

N Dominici, YP Ivanenko, G Cappellini, A d'Avella… - Science, 2011 - science.org
How rudimentary movements evolve into sophisticated ones during development remains
unclear. It is often assumed that the primitive patterns of neural control are suppressed …

Lesion studies in contemporary neuroscience

AR Vaidya, MS Pujara, M Petrides, EA Murray… - Trends in cognitive …, 2019 - cell.com
Studies of humans with focal brain damage and non-human animals with experimentally
induced brain lesions have provided pivotal insights into the neural basis of behavior. As the …