Toward a Detailed Understanding of Base Excision Repair Enzymes:  Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside …

PJ Berti, JAB McCann - Chemical reviews, 2006 - ACS Publications
This review focuses on the chemistry performed by base excision repair (BER) enzymes,
enzymes that remove nucleobases from DNA in the first step of the repair of many types of …

Structural analyses reveal two distinct families of nucleoside phosphorylases

MJ Pugmire, SE Ealick - Biochemical Journal, 2002 - portlandpress.com
The reversible phosphorolysis of purine and pyrimidine nucleosides is an important
biochemical reaction in the salvage pathway, which provides an alternative to the de novo …

Insights into the venom composition of the ectoparasitoid wasp Nasonia vitripennis from bioinformatic and proteomic studies

DC De Graaf, M Aerts, M Brunain… - Insect molecular …, 2010 - Wiley Online Library
With the Nasonia vitripennis genome sequences available, we attempted to determine the
proteins present in venom by two different approaches. First, we searched for the transcripts …

Genes of Bacillus cereus and Bacillus anthracis Encoding Proteins of the Exosporium

SJ Todd, AJG Moir, MJ Johnson, A Moir - Journal of bacteriology, 2003 - Am Soc Microbiol
The exosporium is the outermost layer of spores of Bacillus cereus and its close relatives
Bacillus anthracis and Bacillus thuringiensis. For these pathogens, it represents the surface …

Identification of proteins in the exosporium of Bacillus anthracis

C Redmond, LWJ Baillie, S Hibbs, AJG Moir… - …, 2004 - microbiologyresearch.org
Spores of Bacillus anthracis, the causative agent of anthrax, possess an exosporium. As the
outer surface layer of these mature spores, the exosporium represents the primary contact …

The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

R Masonbrink, TR Maier, U Muppirala, AS Seetharam… - BMC genomics, 2019 - Springer
Background Heterodera glycines, commonly referred to as the soybean cyst nematode
(SCN), is an obligatory and sedentary plant parasite that causes over a billion-dollar yield …

[HTML][HTML] Venom proteins of the parasitoid wasp Nasonia vitripennis: recent discovery of an untapped pharmacopee

EL Danneels, DB Rivers, DC De Graaf - Toxins, 2010 - mdpi.com
Adult females of Nasonia vitripennis inject a venomous mixture into its host flies prior to
oviposition. Recently, the entire genome of this ectoparasitoid wasp was sequenced …

Catalysis by nucleoside hydrolases

W Versées, J Steyaert - Current Opinion in Structural Biology, 2003 - Elsevier
Nucleoside hydrolases cleave the N-glycosidic bond of ribonucleosides. Because of their
vital role in the protozoan purine salvage pathway, nucleoside hydrolases from parasitic …

Nucleoside hydrolase from Leishmania major: cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-Å crystal structure

W Shi, VL Schramm, SC Almo - Journal of Biological Chemistry, 1999 - ASBMB
Protozoan parasites lack the pathway of thede novo synthesis of purines and depend on
host-derived nucleosides and nucleotides to salvage purines for DNA and RNA synthesis …

Cross-Protective Efficacy of a Prophylactic Leishmania donovani DNA Vaccine against Visceral and Cutaneous Murine Leishmaniasis

I Aguilar-Be, R da Silva Zardo… - Infection and …, 2005 - Am Soc Microbiol
The fucose-mannose ligand (FML) complex of Leishmania donovani is a promising vaccine
candidate against murine and canine visceral leishmaniasis, and its main component is a 36 …