Cognitive deficits are a core aspect of psychotic disorders; however, it is not clear to which
extent different pharmacological treatments could distinctly impact these outcomes. Hence …

Antipsychotic drugs (APDs) are best classified as typical or atypical. The distinction is based
solely on their ability to cause extrapyramidal side effects (EPS), including tardive dyskinesia …

Context Neurocognitive impairment in schizophrenia is severe and is an important predictor
of functional outcome. The relative effect of the second-generation (atypical) antipsychotic …

This chapter recounts efforts to dissect the cellular and circuit basis of a memory system in
the primate cortex with the goal of extending the insights gained from the study of normal …

Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of
this impairment are evident in childhood. The cognitive disability is nearly fully developed at …

Objective To investigate the effect of second‐generation antipsychotics on cognitive function
in patients diagnosed with schizophrenia or schizoaffective disorder. Method Multiple …

Background Stress can exacerbate a number of psychiatric disorders, many of which are
associated with prefrontal cortical (PFC) cognitive deficits. Biochemical studies demonstrate …

Treatment-resistant schizophrenia is the object of intense interest because of recent
developments in its treatment and aetiology. The actual definition of treatment-resistant …

Serotonin (5-HT)-receptor-based mechanisms have been postulated to play a critical role in
the action of the new generation of antipsychotic drugs (APDs) that are usually referred to as …

Cognitive deficits are a fundamental feature of the psychopathology of schizophrenia. Yet
the effect of treatment on this dimension of the illness has been unclear. Atypical …