Emerging mechanisms of cardiovascular protection for the omega-3 fatty acid eicosapentaenoic acid
Patients with well-controlled LDL (low-density lipoprotein) levels still have residual
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …
Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?
C Bailly, G Vergoten - Pharmacology & therapeutics, 2020 - Elsevier
Safe and efficient drugs to combat the current COVID-19 pandemic are urgently needed. In
this context, we have analyzed the anti-coronavirus potential of the natural product …
this context, we have analyzed the anti-coronavirus potential of the natural product …
Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia
Background Patients with elevated triglyceride levels are at increased risk for ischemic
events. Icosapent ethyl, a highly purified eicosapentaenoic acid ethyl ester, lowers …
events. Icosapent ethyl, a highly purified eicosapentaenoic acid ethyl ester, lowers …
Role of omega-3 fatty acids in cardiovascular disease: the debate continues
Abstract Purpose of Review The omega-3 fatty acids (n3-FAs), eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …
Effects of icosapent ethyl on total ischemic events: from REDUCE-IT
Background: In time-to-first-event analyses, icosapent ethyl significantly reduced the risk of
ischemic events, including cardiovascular death, among patients with elevated triglycerides …
ischemic events, including cardiovascular death, among patients with elevated triglycerides …
Unmet need for adjunctive dyslipidemia therapy in hypertriglyceridemia management
Despite the important role of high-intensity statins in reducing atherosclerotic cardiovascular
disease events in secondary and primary prevention, substantial residual risk persists …
disease events in secondary and primary prevention, substantial residual risk persists …
Modulation of endothelium function by fatty acids
R Mallick, AK Duttaroy - Molecular and cellular biochemistry, 2022 - Springer
The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …
Dietary fatty acids fine-tune Piezo1 mechanical response
LO Romero, AE Massey, AD Mata-Daboin… - Nature …, 2019 - nature.com
Mechanosensitive ion channels rely on membrane composition to transduce physical stimuli
into electrical signals. The Piezo1 channel mediates mechanoelectrical transduction and …
into electrical signals. The Piezo1 channel mediates mechanoelectrical transduction and …
Prevention of cardiovascular events and mortality with icosapent ethyl in patients with prior myocardial infarction
Background REDUCE-IT was a double-blind trial that randomized 8,179 statin-treated
patients with controlled low-density lipoprotein cholesterol and moderately elevated …
patients with controlled low-density lipoprotein cholesterol and moderately elevated …
New insights into mechanisms of action for omega-3 fatty acids in atherothrombotic cardiovascular disease
R Preston Mason - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Treatment of hypercholesterolemia with statins results in
significant reductions in cardiovascular risk; however, individuals with well-controlled low …
significant reductions in cardiovascular risk; however, individuals with well-controlled low …