Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Myelin is a multilayer lipid membrane structure that wraps and insulates axons, allowing for
the efficient propagation of action potentials. During developmental myelination of the …

Therapeutic approaches to metabolic syndrome (MetS) are numerous and may target
lipoproteins, blood pressure or anthropometric indices. Peroxisome proliferator-activated …

Alzheimer's disease (AD) should be regarded as a degenerative metabolic disease caused
by brain insulin resistance and deficiency, and overlapping with the molecular, biochemical …

▪ Abstract The peroxisome proliferator-activated receptors (PPARs) are a group of three
nuclear receptor isoforms, PPARγ, PPARα, and PPARδ, encoded by different genes. PPARs …

Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Multiple sclerosis is a common cause of neurological disability in young adults. The disease
is complex—its aetiology is multifactorial and largely unknown; its pathology is …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act
as ligand-activated transcription factors. PPAR agonists have well-documented anti …

Peroxisome proliferator activated receptors (PPARs) are transcriptional factors belonging to
the ligand-activated nuclear receptor superfamily. They are ubiquitously expressed …

Peroxisome proliferator-activated and retinoid X receptors (PPARs and RXRs) are
transcription factors belonging to the steroid hormone receptor superfamily. Upon activation …