[HTML][HTML] Mechanistic Insights and Therapeutic Applications of Hinokitiol in Inflammation, Antimicrobial Therapy, and Cancer
KK Karunakar, BV Cheriyan, R Velmurugan… - Pharmacological …, 2024 - Elsevier
Abstract Background Hinokitiol (β-thujaplicin), a naturally occurring tropolone derivative,
exhibits multifaceted pharmacological properties. The aim of this review is to explore the …
exhibits multifaceted pharmacological properties. The aim of this review is to explore the …
Inhibition of beta-catenin shows therapeutic potential in head and neck squamous cell carcinoma in vitro
T Maier, S Stoiber, E Gurnhofer, M Haas… - European Archives of …, 2023 - Springer
Beta-catenin is known to be a vital component of the canonical Wnt signaling cascade,
involved in the carcinogenesis of different solid tumors. We aimed to evaluate the effects of …
involved in the carcinogenesis of different solid tumors. We aimed to evaluate the effects of …
The ATR inhibitor berzosertib acts as a radio-and chemosensitizer in head and neck squamous cell carcinoma cell lines
J Schnoell, C Sparr, S Al-Gboore, M Haas… - Investigational New …, 2023 - Springer
Alterations in the DNA damage response play a crucial role in radio-and chemoresistance of
neoplastic cells. Activation of the Ataxia telangiectasia and Rad3-related (ATR) pathway is …
neoplastic cells. Activation of the Ataxia telangiectasia and Rad3-related (ATR) pathway is …
Quality by design based synthesis and characterization of novel maleyl functionalized albumin solid dry powder for pulmonary targeting
VV Agnihotri, AP Gorle - Drying Technology, 2024 - Taylor & Francis
Dry powder inhalers (DPIs) are propellant-free portable devices used to provide medicines
to the lung. Lactose monohydrate is the most common drug carrier for DPIs. However, the …
to the lung. Lactose monohydrate is the most common drug carrier for DPIs. However, the …
LKB1 Mutations Enhance Radiosensitivity in Non-Small Cell Lung Cancer Cells by Inducing G2/M Cell Cycle Phase Arrest
Y Yao, X Qiu, M Chen, Z Qin, X Zhang… - Current Molecular …, 2024 - ingentaconnect.com
Background: Radiosensitivity remains an important factor affecting the clinical outcome of
radiotherapy for non-small cell lung cancer (NSCLC). Liver kinase B1 (LKB1) as a tumor …
radiotherapy for non-small cell lung cancer (NSCLC). Liver kinase B1 (LKB1) as a tumor …
LncRNA TEX41 promotes the proliferation and migration of squamous cell carcinoma cells by upregulating Atg5 via sponging miR-153-3p
W Yang, Y Chen - Cellular and Molecular Biology, 2023 - cellmolbiol.org
This study was conducted to investigate if lncRNA TEX41 could have effects on SCC. The
aim was to confirm that TEX41 could promote SCC progression by up-regulating Atg5 via …
aim was to confirm that TEX41 could promote SCC progression by up-regulating Atg5 via …