Dearomatization reactions provide rapid access to structurally complex three-dimensional
molecules from simple aromatic compounds. Plenty of reports have demonstrated their …

Dearomatisation reactions of (hetero) arenes have been widely employed as efficient
methods to obtain highly substituted saturated cyclic compounds for over a century. In recent …

Prenylated and reverse-prenylated indolines are privileged scaffolds in numerous naturally
occurring indole alkaloids with a broad spectrum of important biological properties …

Benzothiazolines, with their versatile nature, serve as fundamental building blocks for the
synthesis of significant biological compounds. However, methods for the preparation of …

The rapid preparation of complex three‐dimensional (3D) heterocyclic scaffolds is a key
challenge in modern medicinal chemistry. Despite the increased probability of clinical …

Bridged benzazepine scaffolds, possessing unique structural and physicochemical
activities, are widespread in various natural products and drugs. The construction of these …

Reactions that lead to destruction of aromatic ring systems often require harsh conditions
and, thus, take place with poor selectivities. Selective partial dearomatization of fused …

A photoredox-catalyzed intermolecular dearomative trifluoromethylcarboxylation of indoles
and heteroanalogues with CO2 and fluorinated radical precursors has been achieved. A …

Disclosed here is a visible-light photoredox-catalyzed intermolecular sequential α-
aminomethyl/carboxylative dearomatization of indoles with CO2 and α-aminoalkyl radical …

Samarium diiodide (SmI2) mediated reductive coupling reactions are powerful methods for
the construction of carbon–carbon bond in organic synthesis. Despite the extensive …