Phage display

GP Smith, VA Petrenko - Chemical reviews, 1997 - ACS Publications
In crossing a heath, suppose... I had found a watch upon the ground, and it should be
inquired how the watch happened to be in that place....[T] he inference, we think, is …

Review of phage display: A jack-of-all-trades and master of most biomolecule display

BPC Song, ACW Ch'ng, TS Lim - International Journal of Biological …, 2024 - Elsevier
Phage display was first described by George P. Smith when it was shown that virus particles
were capable of presenting foreign proteins on their surface. The technology has paved the …

Phage-display technology–finding a needle in a vast molecular haystack

DJ Rodi, L Makowski - Current opinion in biotechnology, 1999 - Elsevier
Screening of phage-displayed libraries of proteins and peptides has, for nearly a decade,
proven to be a highly effective method for finding much needed 'needles' in a vast molecular …

Phage display systems and their applications

M Paschke - Applied microbiology and biotechnology, 2006 - Springer
Screening phage display libraries of proteins and peptides has, for almost two decades,
proven to be a powerful technology for selecting polypeptides with desired biological and …

Biotechnological applications of phage and cell display

I Benhar - Biotechnology advances, 2001 - Elsevier
In recent years, the use of surface-display vectors for displaying polypeptides on the surface
of bacteriophage and bacteria, combined with in vitro selection technologies, has …

Protein design and phage display

RH Hoess - Chemical Reviews, 2001 - ACS Publications
The application of phage display for de novo design of proteins appears at first to be an
unusual combination of technologies. Recently, however, the power of combining the …

Bacterial cell surface display of an enzyme library for selective screening of improved cellulase variants

YS Kim, HC Jung, JG Pan - Applied and Environmental …, 2000 - Am Soc Microbiol
The bacterial surface display method was used to selectively screen for improved variants of
carboxymethyl cellulase (CMCase). A library of mutated CMCase genes generated by DNA …

Phage display

DR Burton - Immunotechnology, 1995 - Elsevier
Phage display is a powerful method for the selection and evolution of proteins and peptides.
Applications include the generation of potent and novel antibodies, the in vitro improvement …

[图书][B] Phage display in biotechnology and drug discovery

SS Sidhu, CR Geyer - 2015 - books.google.com
The book provides a comprehensive view of the impact and promise of phage display in
drug discovery and biotechnology. Building on the success of its previous edition, the book …

Phage display: protein engineering by directed evolution

KT O'Neil, RH Hoess - Current opinion in structural biology, 1995 - Elsevier
Phage display of proteins has become an important tool for protein engineering. Over the
past year, the versatility of the technology has expanded to include the development of DNA …