The extracellular matrix (ECM) is the complex meshwork of proteins and glycans that forms
the scaffold that surrounds and supports cells. It exerts key roles in all aspects of metazoan …

Peroxidasin (PXDN) is a secreted heme peroxidase that catalyzes the oxidative crosslinking
of collagen IV within the extracellular matrix (ECM) via intermediate hypobromous acid …

Introduction The extracellular matrix (ECM) is a highly organized and dynamic network of
proteins and glycosaminoglycans that provides critical structural, mechanical, and …

Obesity has reached epidemic proportions in the United States, emerging as a risk factor for
the onset of breast cancer and a harbinger of unfavorable outcomes [1],[2],[3]. Despite …

Basement membranes (BMs) are thin layers of extracellular matrix that separate epithelia,
endothelia, muscle cells, and nerve cells from adjacent interstitial connective tissue. BMs are …

Basement membranes are sheets of extracellular matrix separating tissue layers and
providing mechanical support. Their mechanical properties are determined largely by their …