The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

Ynamide, a unique species with inherited polarization of nitrogen lone pair electron to triple
bond, has been largely used for the developement of novel synthetic methods and the …

Ynamides consisting of an electron-withdrawing group on the nitrogen atom have proven to
be powerful and versatile building blocks that are involved in a variety of useful chemical …

In the past decades, significant advances have been made on radical Smiles
rearrangement. However, the eventually formed radical intermediates in these reactions are …

Bridged frameworks are of high chemical and biological significance, being ubiquitous in
pharmaceutical molecules and natural products. Specific structures are usually preformed to …

Here, we report a copper‐catalyzed asymmetric cascade cyclization/[1, 2]‐Stevens‐type
rearrangement via a non‐diazo approach, leading to the practical and atom‐economic …

Described herein is a novel Brønsted acid catalyzed intramolecular hydroalkoxylation/
Claisen rearrangement, allowing the practical and atom‐economic synthesis of a range of …

A regiodivergent oxidative cyclization of ynamide-tethered benzaldehydes has been
achieved using an organocatalytic approach based on NHC/base. The method enables the …

Here an efficient copper‐catalyzed cascade cyclization of azide‐ynamides via α‐imino
copper carbene intermediates is reported, representing the first generation of α‐imino …

Medium‐sized N, S‐heterocycles have received tremendous interest due to their biological
activities and potential medical applications. However, asymmetric synthesis of these …