Genomic scans of multiple populations often reveal marker loci with greatly increased
differentiation between populations. Often this differentiation coincides in space with …

Evolution in allopatric populations can lead to incompatibilities that result in reduced hybrid
fitness and ultimately reproductive isolation upon secondary contact. The D obzhansky–M …

Reduced fitness in interpopulation hybrids can be a first indication of genetic
incompatibilities that may ultimately lead to reproductive isolation and speciation. A growing …

Mitochondrial transcription, translation, and respiration require interactions between genes
encoded in two distinct genomes, generating the potential for mutations in nuclear and …

Mitochondria are key to energy conversion in virtually all eukaryotes. Intriguingly, despite
billions of years of evolution inside the eukaryote, mitochondria have retained their own …

Mitochondrial diseases [often caused by mutations in mitochondrial DNA (mtDNA)] can
manifest in a range of severe symptoms, for which there are currently no cures. The …

The mitochondrial genome is a fundamental component of the eukaryotic domain of life,
encoding for several important subunits of the respiratory chain, the main energy production …

Dietary restriction (DR) is the most consistent means of extending longevity in a wide range
of organisms. A growing body of literature indicates that mitochondria play an important role …

Two major inconsistencies exist in the current neo-Darwinian evolutionary theory that
random chromosomal mutations acted on by natural selection generate new species. First …

Aerobic metabolism in eukaryotic cells requires extensive interactions between products of
the nuclear and mitochondrial genomes. Rapid evolution of the mitochondrial genome …