Disseminated intravascular coagulation (DIC) is a systemic activation of the coagulation
system, which results in microvascular thrombosis and, simultaneously, potentially life …

Hyperleukocytosis, arbitrarily defined in acute leukemia as a white blood cell count greater
than 100,000/mL, often is associated with increased morbidity and mortality in patients with …

Retrospective studies have suggested that older adolescents and young adults (AYAs) with
acute lymphoblastic leukemia (ALL) have better survival rates when treated using a pediatric …

Hyperleukocytosis (HL) per se is a laboratory abnormality, commonly defined by a white
blood cell count> 100 000/µL, caused by leukemic cell proliferation. Not the high blood …

Tissue factor (TF) is a procoagulant protein released from activated host cells, such as
monocytes, and tumor cells on extracellular vesicles (EVs). TF+ EVs are observed in the …

Venous thromboembolism is a common complication in patients with cancer, but only limited
data are available in acute myeloid leukemia (AML). In a prospective study in a cohort of 272 …

The American Cancer Society estimated that 13,800 cases of acute myelogenous leukemia
(AML) and 6000 cases of acute lymphoblastic leukemia (ALL) were diagnosed in the United …

The American Cancer Society estimated that 13,800 cases of acute myelogenous leukemia
(AML) and 6000 cases of acute lymphoblastic leukemia (ALL) were diagnosed in the United …

Introduction Hyperleukocytosis, defined as a total white blood cell count (WBC)> 50 or more
commonly> 100× 109 cells/L, is a presenting feature of acute myeloid leukemia (AML) in …

Disseminated intravascular coagulation (DIC) significantly contributes to the bleeding and
thrombotic complications in patients with hematologic malignancies. As shown in other …