Flavonoids as potential anti-inflammatory molecules: A review

JM Al-Khayri, GR Sahana, P Nagella, BV Joseph… - Molecules, 2022 - mdpi.com
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Adjunctive silymarin supplementation and its effects on disease severity, oxidative stress, and inflammation in patients with Alzheimer's disease

SM Navabi, D Elieh-Ali-Komi, D Afshari… - Nutritional …, 2024 - Taylor & Francis
ABSTRACT Background Brain tissue in Alzheimer's patients is exposed to oxidative stress.
Silymarin is an adjunct drug that has anti-inflammatory and antioxidant properties. Objective …

[HTML][HTML] Differential accumulation of silymarin induced by exposure of Silybum marianum L. callus cultures to several spectres of monochromatic lights

M Younas, S Drouet, M Nadeem… - … of Photochemistry and …, 2018 - Elsevier
Silybum marianum L.(Milk thistle) is one of the most extensively studied medicinal herbs with
well-known hepatoprotective activity. Light is considered as a key abiotic elicitor influencing …

Phyto‐pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID‐19, based on its promising immunomodulatory, anti …

P Palit, A Mukhopadhyay… - Phytotherapy …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) triggered by a new viral pathogen, named severe
acute respiratory syndrome Coronavirus‐2 (SARS‐CoV‐2), is now a global health …

Exploring the molecular mechanisms and shared potential drugs between rheumatoid arthritis and arthrofibrosis based on large language model and synovial …

Z Wei, X Chen, Y Sun, Y Zhang, R Dong, X Wang… - Scientific Reports, 2024 - nature.com
Rheumatoid arthritis (RA) and arthrofibrosis (AF) are both chronic synovial hyperplasia
diseases that result in joint stiffness and contractures. They shared similar symptoms and …

Interactive Effects of Light and Melatonin on Biosynthesis of Silymarin and Anti-Inflammatory Potential in Callus Cultures of Silybum marianum (L.) Gaertn.

M Shah, MA Ullah, S Drouet, M Younas… - Molecules, 2019 - mdpi.com
Silybum marianum (L.) Gaertn. is a well-known medicinal herb, primarily used in liver
protection. Light strongly affects several physiological processes along with secondary …

The Effect of Oral Administration of Silymarin on Serum Levels of Tumor Necrosis Factor-α and Interleukin-1ß in Patients with Rheumatoid Arthritis

M Shavandi, Y Yazdani, S Asar… - Iranian Journal of …, 2022 - iji.sums.ac.ir
Background: Rheumatoid Arthritis (RA) is a systemic chronic autoimmune disease. Several
inflammatory agents play key roles in RA pathogenesis, among which tumor necrosis factor …

The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial

M Mirnezami, H Jafarimanesh… - Dermatologic …, 2020 - Wiley Online Library
The aim of the present study was to investigate the effect of silymarin (Livergol) on liver
enzymes in patients taking isotretinoin (Roaccutane). In this double‐blind clinical trial, 74 …

Oxidative Stress Mediated Therapy in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

K Djordjevic, A Milojevic Samanovic, M Veselinovic… - Antioxidants, 2023 - mdpi.com
Objective: The aim of this meta-analysis is to explore all the available literature to obtain
updated data about the potential use of antioxidants in the treatment of rheumatoid arthritis …