Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …

Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …

Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …

Pathogens including viruses, bacteria, fungi, and parasites continue to shape our lives in
profound ways every day. As we have learned to live in parallel with pathogens, we have …

Synthetic polymers have been extensively exploited for biomedical and pharmacological
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …

Galectin-3 is the only chimeric representative of the galectin family. Although galectin-3 has
ubiquitous regulatory and physiological effects, there is a great number of pathological …

Galectin-3 (Gal-3) participates in many cancer-related metabolic processes. The inhibition of
overexpressed Gal-3 by, eg, β-galactoside-derived inhibitors is hence promising for cancer …

Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …

Galectins are a family of carbohydrate-binding lectins modulating cell events such as cell
proliferation, apoptosis, adhesion or migration by cross-linking the glycan structures of cell …

Sulfated glycosaminoglycans (sGAGs) such as heparan sulfate (HS) are structurally diverse
linear polysaccharides that are involved in many biological processes and have gained …