Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge

A Dima, C Jurcut, F Chasset… - Therapeutic …, 2022 - journals.sagepub.com
The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …

The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?

EQ Roldan, G Biasiotto, P Magro, I Zanella - Pharmacological research, 2020 - Elsevier
The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine
(HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti …

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

G Ruiz-Irastorza, M Ramos-Casals… - Annals of the …, 2010 - ard.bmj.com
Background: Antimalarial drugs (AMs), chloroquine (CQ) and hydroxychloroquine (HCQ),
are frequently withdrawn in patients with lupus with either severe or remitting disease …

The antiphospholipid syndrome in patients with systemic lupus erythematosus

GJ Pons-Estel, L Andreoli, F Scanzi, R Cervera… - Journal of …, 2017 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
occurrence of venous and/or arterial thrombosis and pregnancy morbidity in the presence of …

The role of antimalarial agents in the treatment of SLE and lupus nephritis

SJ Lee, E Silverman, JM Bargman - Nature Reviews Nephrology, 2011 - nature.com
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that affects
various organs. Lupus nephritis is one of the most common, and most important, serious …

Effect of antimalarials on thrombosis and survival in patients with systemic lupus erythematosus

G Ruiz-Irastorza, MV Egurbide, JI Pijoan… - Lupus, 2006 - journals.sagepub.com
Antimalarials have shown beneficial effects on systemic lupus erythematosus (SLE) activity.
Our aim was to investigate whether antimalarials protect against thrombosis and influence …

The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual

BJ Fessler, GS Alarcón, G McGwin Jr… - Arthritis & …, 2005 - Wiley Online Library
Objective To examine whether hydroxychloroquine (HCQ) usage is associated with a
reduced risk of damage accrual in patients with systemic lupus erythematosus (SLE) …

Mortality, causes of death and influence of medication use in patients with systemic lupus erythematosus vs matched controls

IEM Bultink, F De Vries, RF Van Vollenhoven… - …, 2021 - academic.oup.com
Objectives We wanted to estimate the magnitude of the risk from all-cause, cause-specific
and sex-specific mortality in patients with SLE and relative risks compared with matched …

Hydroxychloroquine: a multifaceted treatment in lupus

N Costedoat-Chalumeau, B Dunogue, N Morel… - La Presse Médicale, 2014 - Elsevier
The efficacy of antimalarials, especially hydroxychloroquine (HCQ), in preventing systemic
lupus erythematosus (SLE) flares is well demonstrated. However, many studies show that …