Membraneless compartments, such as complex coacervates, have been hypothesized as
plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their …

Diazeniumdiolate ions of structure R2N [N (O) NO]-(1) are of pharmacological interest
because they spontaneously generate the natural bioregulatory species, nitric oxide (NO) …

The hairpin ribozyme is a small catalytic RNA that achieves an active configuration by
docking of its two helical domains in an antiparallel fashion. Both docking and subsequent …

The rapidly emerging interest in the evaluation of biogenic amines especially spermidine
and spermine has brought up new demands for the efficacious technical methods. These …

Nucleoside phosphoramidates have recently received considerable interest as pro-drugs of
antiviral analogs of nucleoside monophosphates and as constituents of antisense …

This paper describes chemical synthesis of prolyl PNAs which are a class of
conformationally constrained chiral PNA analogues. The monomers are derived from …

Peptide Nucleic Acids (PNAs), the achiral DNA mimics with amide backbone, are emerging
as attractive leads for drug development by antisense approach. Two major limitations of …

The preparation of tetracationic metalloporphyrin precursors for the attachement to DNA
binding molecules is reported. Based on a D 4 h tetrapyridylporphyrin, such precursors are …

The effect of surfactant micelles on the acid-catalyzed dissociation of NO from
diazeniumdiolate ions of structure R1R2N [N (O) NO]-has been examined in phosphate …

The successful separation of tosylated polyamines putrecine (PUT), cadaverine (CAD)
spermidine (SPD) and spermine (SPM) by high-performance capillary zone electrophoresis …