Lactones: Classification, synthesis, biological activities, and industrial applications

SK Sartori, MAN Diaz, G Diaz-Muñoz - Tetrahedron, 2021 - Elsevier
This review summarizes the current knowledge on lactones, a class of biologically active
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …

The potential of secondary metabolites from plants as drugs or leads against trypanosoma cruzi-an update from 2012 to 2021

H Barbosa, F Thevenard… - Current Topics in …, 2023 - ingentaconnect.com
Background: Chagas disease (American Trypanosomiasis) is classified by the World Health
Organization (WHO) as one of the seventeen neglected tropical diseases (NTD), affecting …

Gold Self‐Relay Catalysis Enabling [3, 3]‐Sigmatropic Rearrangement/Nazarov Cyclization and Allylic Alkylation Cascade for Constructing All‐Carbon Quaternary …

FT Meng, XY Qin, J Li, TS Zhang, SJ Tu… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Molecular scaffolds endowed with all‐carbon quaternary
stereocenter are ubiquitous in natural products and significant bioactive molecules …

Advances in the properties of incomptine a: cytotoxic activity and downregulation of hexokinase II in breast cancer cell lines

AG Arietta-García, F Calzada… - International Journal of …, 2023 - mdpi.com
Breast cancer treatments are limited by the cancer subtype and its selectivity towards tumor
cells, hence the importance of finding compounds that increase the survival of healthy cells …

Production of lactones for flavoring and pharmacological purposes from unsaturated lipids: An industrial perspective

N Syed, S Singh, S Chaturvedi… - Critical Reviews in …, 2023 - Taylor & Francis
The enantiomeric pure and natural (+)-Lactones (C≤ 14) with aromas obtained from fruits
and milk are considered flavoring compounds. The flavoring value is related to the lactones' …

The anti‐Trypanosoma activities of medicinal plants: A systematic review of the literature

S Nekoei, F Khamesipour… - Veterinary Medicine …, 2022 - Wiley Online Library
Background The existing drug treatments for trypanosomiases are limited and suffer from
shortcomings due to their toxicity and the emergence of resistant parasites. Developing anti …

[HTML][HTML] Plinia cauliflora (Mart.) Kausel (Jaboticaba) leaf extract: In vitro anti-Trypanosoma cruzi activity, toxicity assessment and phenolic-targeted UPLC-MSE …

BVD Galvão, CF Araujo-Lima, MCP Dos Santos… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Plinia cauliflora (Mart.) Kausel, known as
Brazilian grape or jaboticaba, is widely used in Brazilian traditional medicine to treat …

What dominates the changeable pharmacokinetics of natural sesquiterpene lactones and diterpene lactones: A review focusing on absorption and metabolism

Z Yu, Z Chen, Q Li, K Yang, Z Huang… - Drug Metabolism …, 2021 - Taylor & Francis
Sesquiterpene lactones (STLs) and diterpene lactones (DTLs) are two groups of common
phytochemicals with similar structures. It's frequently reported that both exhibit changeable …

[HTML][HTML] Microalgae extracts: Potential anti-Trypanosoma cruzi agents?

R Veas, M Rojas-Pirela, C Castillo, C Olea-Azar… - Biomedicine & …, 2020 - Elsevier
Introduction Chagas disease, caused by the protozoan parasiteTrypanosoma cruzi, has no
effective treatment available. On the other hand, microalgae are aquatic organisms that …

Ethnopharmacology of the Asteraceae family in Mexico

VG Cilia-López, R Cariño-Cortés… - Botanical …, 2021 - scielo.org.mx
Abstract Background: In Mexico, the Asteraceae are part of traditional knowledge where its
members have several uses, but they are particularly remarkable in traditional medicine and …