Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Plants containing resveratrol have been used effectively in traditional medicine for over
2000 years. It can be found in some plants, fruits, and derivatives, such as red wine …

Intermittent fasting (IF) can improve function and health during aging in laboratory model
organisms, but the mechanisms at work await elucidation. We subjected fruit flies …

Aging is the major risk factor for neurodegenerative diseases, accelerated by excessive
calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent …

Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …

With increasing feasibility of predicting conversion of mild cognitive impairment to dementia
based on biomarker profiling, the urgent need for efficacious disease‐modifying compounds …

Alzheimer's disease (AD) is a highly age-related cognitive decline frequently attacking the
elderly. Senescence-accelerated mouse-prone 8 (SAMP8) is an ideal model to study AD …

The calorie restriction paradigm has provided one of the most widely used and most useful
tools for investigating mechanisms of aging and longevity. By far, rodent models have been …

Recent findings have revealed a novel inflammatory mechanism that contributes to tissue
injury in cerebral ischemia mediated by multi-protein complexes termed inflammasomes …

A Mediterranean diet rich in olive oil has been associated with health benefits in humans. It
is unclear if and to what extent olive oil phenolics may mediate these health benefits. In this …