A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced
into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine …

The use of antibiotics is necessary to treat bacterial diseases. Determination of optimal
dosage in the target animals is increasingly being recognized as vital for maximizing efficacy …

Levofloxacin pharmacokinetic profiles were evaluated in 6 healthy female rabbits after
intravenous (I/V), intramuscular (I/M), or subcutaneous (S/C) administration routes at a single …

The aim of this study was to assess the pharmacokinetic profile of LFX in sheep after
intravenous (IV) and oral (PO) administration of 2 mg/kg LFX once a day for 5 days and to …

The pharmacokinetics of levofloxacin (4 mg/kg), administered both alone and in combination
with tolfenamic acid (2 mg/kg) and flunixin meglumine (2.2 mg/kg), was established after …

This study aimed to evaluate the pharmacokinetics/pharmacodynamics (PK/PD) of
levofloxacin in non-lactating goats. Using a randomized cross-over study design, each …

Aim: The aim of this study was to investigate the short-term effect of levofloxacin on the
microbiota of healthy lungs. Material and methods: Male F344 rats received either no …

Pharmacokinetics of levofloxacin in goats, following oral administration (4 mg/kg) was
evaluated in trikatu pretreated goats. Reverse-phase High Performance Liquid …

Antibacterial and NSAIDs are used most frequently in multiple drug prescriptions. It is well
documented that concurrently administered drugs may alter pharmacokinetics of one or both …

This study was conducted to evaluate the cytogenetic effects of levofloxacin in male rats. It
was carried out on fifty four of the albino male rats, they were divided equally into three main …