Stathmin: a protein with many tasks. New biomarker and potential target in cancer

B Belletti, G Baldassarre - Expert opinion on therapeutic targets, 2011 - Taylor & Francis
Introduction: Stathmin is a microtubule-destabilizing phosphoprotein, firstly identified as the
downstream target of many signal transduction pathways. Several studies then indicated …

Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications

L Nie, G Wu, DE Culley, JCM Scholten… - Critical reviews in …, 2007 - Taylor & Francis
Recent advances in high-throughput technologies enable quantitative monitoring of the
abundance of various biological molecules and allow determination of their variation …

Protein profiles associated with survival in lung adenocarcinoma

G Chen, TG Gharib, H Wang… - Proceedings of the …, 2003 - National Acad Sciences
Morphologic assessment of lung tumors is informative but insufficient to adequately predict
patient outcome. We previously identified transcriptional profiles that predict patient survival …

Intrinsic and extrinsic factors affecting microtubule dynamics in normal and cancer cells

F Borys, E Joachimiak, H Krawczyk, H Fabczak - Molecules, 2020 - mdpi.com
Microtubules (MTs), highly dynamic structures composed of α-and β-tubulin heterodimers,
are involved in cell movement and intracellular traffic and are essential for cell division …

Stathmin 1: a novel therapeutic target for anticancer activity

S Rana, PB Maples, N Senzer… - Expert review of …, 2008 - Taylor & Francis
Stathmin 1 (STMN1), also known as p17, p18, p19, 19K, metablastin, oncoprotein 18, LAP
18 and Op18, is a 19 kDa cytosolic protein. It was the first discovered member of a family of …

Upregulated INHBA expression may promote cell proliferation and is associated with poor survival in lung adenocarcinoma

CW Seder, W Hartojo, L Lin, AL Silvers, Z Wang… - Neoplasia, 2009 - Elsevier
Introduction: The expression, mechanisms of regulation, and functional impact of INHBA
(activin A) in lung adenocarcinoma (AD) have not been fully elucidated. Methods: INHBA …

Identification of novel nasopharyngeal carcinoma biomarkers by laser capture microdissection and proteomic analysis

AL Cheng, WG Huang, ZC Chen, F Peng… - Clinical Cancer …, 2008 - AACR
Purpose: To identify novel nasopharyngeal carcinoma (NPC) biomarkers by laser capture
microdissection and a proteomic approach. Experimental Design: Proteins from pooled …

Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells

TY Jeon, ME Han, YW Lee, YS Lee, GH Kim… - British journal of …, 2010 - nature.com
Background: Stathmin1 is a microtubule-regulating protein that has an important role in the
assembly and disassembly of the mitotic spindle. The roles of stathmin1 in carcinogenesis of …

Kif18A is involved in human breast carcinogenesis

C Zhang, C Zhu, H Chen, L Li, L Guo, W Jiang… - …, 2010 - academic.oup.com
Microtubule (MT) kinesin motor proteins orchestrate various cellular processes (eg mitosis,
motility and organelle transportation) and have been implicated in human carcinogenesis …

Stathmin1 overexpression associated with polyploidy, tumor‐cell invasion, early recurrence, and poor prognosis in human hepatoma

SY Hsieh, SF Huang, MC Yu, TS Yeh… - … in cooperation with …, 2010 - Wiley Online Library
Frequent intrahepatic metastasis causes early tumor recurrence and dismaying prognosis of
human hepatocellular carcinoma (HCC). We recently identified overexpression of stathmin1 …