Abstract tRNAs are key adaptor molecules that decipher the genetic code during translation
of mRNAs in protein synthesis. In contrast to the traditional view of tRNAs as ubiquitously …

Unlike other essential trace elements that interact with proteins in the form of cofactors,
selenium (Se) becomes co-translationally incorporated into the polypeptide chain as part of …

Transfer RNAs (tRNAs) have been historically viewed as non-dynamic adaptors that decode
the genetic code into proteins. Recent work has uncovered dynamic regulatory roles for …

Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …

The habitual intake of selenium (Se) varies strongly around the world, and many people are
at risk of inadequate supply and health risks from Se deficiency. Within the human organism …

Selenium has transitioned from an environmental poison and carcinogen to an essential
micronutrient associated with a broad array of health promoting effects. These beneficial …

Transfer RNAs (tRNAs) decode messenger RNA codons to peptides at the ribosome. The
nuclear genome contains many tRNA genes for each amino acid and even each anticodon …

In the past two decades significant progress has been made in uncovering the biological
function of selenium. Selenium, an essential trace element, is required for the biogenesis of …

Abstract Development and differentiation of the thyroid gland is directed by expression of
specific transcription factors in the thyroid follicular cell which mediates hormone …

ABSTRACT Base 37 in tRNA, 3′-adjacent to the anticodon, is occupied by a purine base
that is thought to stabilize codon recognition by stacking interactions on the first Watson …